SCHEMBL21734285

SCHEMBL21734285

COC(=O)N(OC)c1ccccc1CI

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TSPO P30536 2/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 4/20 0.33
KMT2A Q03164 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 2/20 0.32
CYP2D6 P10635 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
EGFR P00533 1/20 0.31
NOX4 Q9NPH5 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10061323 0.87 PTGER1 (0.37) LMNAALDH1A1MAPTTSHRKMT2A
SCHEMBL2371805 0.84 LMNA (0.34) LMNAALDH1A1TSPOMAPTTSHR
SCHEMBL1461137 0.84 ALDH1A1 (0.36) LMNAALDH1A1TSPOMAPTTSHR
SCHEMBL14352104 0.83 TSHR (0.41) ALDH1A1MAPTTSHRKMT2AKDM4E
SCHEMBL13499618 0.83 PPARD (0.39) LMNAALDH1A1KMT2AMTNR1AMTNR1B
SCHEMBL6130271 0.81 IDO1 (0.46) ALDH1A1ATM
SCHEMBL14351893 0.80 APP (0.43) LMNAALDH1A1MAPTKMT2AKDM4E
SCHEMBL23367890 0.78 KMT2A (0.35) LMNAALDH1A1MAPTTSHRKMT2A
SCHEMBL21734286 0.77 NISCH (0.42) ALDH1A1TSPOMAPTTSHRKDM4E
SCHEMBL14351850 0.77 MEN1 (0.51) ALDH1A1TSHRKMT2AKDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020034181-A9 QUATERNARY TRIPHENYLPHOSPHONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF 中国农业大学 2020-08-13 WO disclosed
WO-2020034181-A1 QUATERNARY TRIPHENYLPHOSPHONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF 中国农业大学 2020-02-20 WO disclosed