Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13654745 | 0.86 | PRKCI (0.57) | PRKCIPKMCREBBPSLC6A4SLC6A2 | |
| SCHEMBL7642028 | 0.86 | GAA (0.49) | SLC6A4SLC6A2SLC6A3KCNH2HTT | |
| SCHEMBL8340727 | 0.81 | PKM (0.66) | PRKCIPKMSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14589542 | 0.79 | PKM (0.49) | PRKCIPKMCREBBPHTTKMT2A | |
| SCHEMBL6376548 | 0.79 | ALOX15 (0.45) | SLC6A4SLC6A2SLC6A3KCNH2HTR2A | |
| SCHEMBL11620152 | 0.77 | ALDH1A1 (0.64) | PRKCIPKMCREBBPSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL11620283 | 0.76 | ALDH1A1 (0.67) | PRKCIPKMCREBBPSLC6A4SLC6A2 | |
| SCHEMBL15087363 | 0.76 | CREBBP (0.49) | PRKCIPKMCREBBPHTTKMT2A | |
| Hydrochloric Acid SCHEMBL11619988 | 0.75 | LMNA (0.40) | PRKCICREBBPPOLB | |
| SCHEMBL14589544 | 0.75 | HTT (0.47) | PRKCIPKMCREBBPHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207179-B2 | Substituted indolines as tyrosine kinase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-26 | — | — | US | disclosed |
| US-20100222331-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222331-A1 | NEW COMPOUNDS | CCNA1, CCNY, MKI67 | PRKCI 2435/4885PKM 1535/4885CREBBP 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.