Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063274 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL29018537 | 0.74 | KIF11 (0.53) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL13349837 | 0.74 | POLB (0.40) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL10063705 | 0.73 | SIRT1 (0.54) | SMN1; SMN2NPC1ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL14922485 | 0.73 | NPC1 (0.59) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL10063269 | 0.73 | KDM4E (0.51) | SMN1; SMN2KDM4EALDH1A1GABRA1HSD17B10 | |
| SCHEMBL10063355 | 0.72 | MAPT (0.46) | SMN1; SMN2KDM4EALDH1A1RAB9AHSD17B10 | |
| SCHEMBL13071245 | 0.72 | NPC1 (0.58) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL2056350 | 0.71 | LMNA (0.59) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL5494899 | 0.71 | KIF11 (0.62) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364951-B1 | Triazoquinolone derivatives as pest controllers | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |