Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720917 | 0.80 | GHSR (0.47) | SMN1; SMN2HSD17B10CYP2D6GABRA1 | |
| SCHEMBL10063205 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL10063269 | 0.77 | KDM4E (0.51) | SMN1; SMN2KDM4EALDH1A1HSD17B10GABRA1 | |
| SCHEMBL10063705 | 0.77 | SIRT1 (0.54) | SMN1; SMN2NPC1ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL23786255 | 0.75 | MEN1 (0.58) | SMN1; SMN2KDM4ENPC1ALDH1A1HTT | |
| SCHEMBL26171264 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10GABRA1GABRB2 | |
| SCHEMBL10063356 | 0.74 | KDM4E (0.47) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL11955040 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL20274465 | 0.72 | HTT (0.60) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL21025331 | 0.72 | CA12 (0.46) | SMN1; SMN2KDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364951-B1 | Triazoquinolone derivatives as pest controllers | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |