Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13960961 | 0.81 | SIRT1 (0.82) | SIRT1LMNACYP1A2GAAHPGD | |
| SCHEMBL10063269 | 0.81 | KDM4E (0.51) | LMNAGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10063356 | 0.79 | KDM4E (0.47) | LMNAGAACYP2D6MEN1KMT2A | |
| SCHEMBL2720917 | 0.79 | GHSR (0.47) | PTGS2CYP2D6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20274465 | 0.77 | HTT (0.60) | LMNACYP1A2GAAHPGDCYP2D6 | |
| SCHEMBL10063274 | 0.77 | SMN1; SMN2 (0.42) | CYP2D6ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31490922 | 0.75 | LMNA (0.60) | LMNACYP1A2GAAHPGDMEN1 | |
| SCHEMBL13979604 | 0.73 | SIRT1 (0.68) | SIRT1L3MBTL1MEN1KMT2AHTR6 | |
| SCHEMBL8020349 | 0.73 | PDE10A (0.64) | LMNACYP1A2HPGDPTGS2CYP2D6 | |
| SCHEMBL10063205 | 0.73 | SMN1; SMN2 (0.50) | L3MBTL1MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364951-B1 | Triazoquinolone derivatives as pest controllers | MEIJI SEIKA PHARMA CO LTD (JP) | 2012-05-02 | — | — | EP | disclosed |