SCHEMBL10064083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10040412	0.95	TDP1 (0.53)	TDP1RXFP1TRPV1POLBL3MBTL1
	SCHEMBL67919	0.83	MEN1 (0.61)	TDP1RXFP1POLBL3MBTL1ALDH1A1
	SCHEMBL13609717	0.82	TDP1 (0.57)	TDP1RXFP1POLBL3MBTL1RECQL
	SCHEMBL124216	0.81	RXFP1 (0.65)	TDP1RXFP1POLBL3MBTL1RECQL
	Hydrochloric Acid SCHEMBL7460090	0.79	RXFP1 (0.62)	TDP1RXFP1POLBL3MBTL1RECQL
	SCHEMBL14904374	0.78	CYP1A2 (0.41)	TDP1TRPV1ALDH1A1MEN1KMT2A
	SCHEMBL216958	0.78	TDP1 (0.70)	TDP1RXFP1TRPV1POLBL3MBTL1
	SCHEMBL5026110	0.78	TRPV1 (0.52)	TRPV1POLBL3MBTL1ALDH1A1MEN1
	SCHEMBL1808467	0.78	MEN1 (0.64)	TDP1POLBL3MBTL1ALDH1A1MEN1
	SCHEMBL14789934	0.78	CYP1A2 (0.43)	TDP1TRPV1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.