Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605603 | 0.86 | ALOX15 (0.44) | ALOX15HSD17B10GRIK1GRIK2GRM1 | |
| SCHEMBL18922729 | 0.81 | SMN1; SMN2 (0.38) | ALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL5175886 | 0.80 | ALOX15 (0.40) | ALOX15HSD17B10ALDH1A1ECE1MEN1 | |
| SCHEMBL5282303 | 0.78 | MCL1 (0.45) | ALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL12081771 | 0.78 | ALDH1A1 (0.43) | ALOX15HSD17B10ALDH1A1CYP2C9HPGD | |
| SCHEMBL2605612 | 0.77 | SMN1; SMN2 (0.43) | ALOX15HSD17B10ALDH1A1HPGDECE1 | |
| SCHEMBL2554762 | 0.77 | ECE1 (0.43) | ALOX15HSD17B10ALDH1A1CYP2C9HPGD | |
| SCHEMBL16802900 | 0.75 | ALOX15 (0.36) | ALOX15HSD17B10ALDH1A1HPGDECE1 | |
| SCHEMBL5288745 | 0.75 | CASP2 (0.47) | ALOX15CYP2C9HPGDMEN1KMT2A | |
| SCHEMBL11345101 | 0.75 | ALOX15 (0.43) | ALOX15HSD17B10GRIK1GRIK2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052163-A1 | DENTAL CEMENT COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |