SCHEMBL2605603

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5175886	0.88	ALOX15 (0.40)	ALOX15HSD17B10ECE1TET2TET3
	SCHEMBL10065799	0.86	ALOX15 (0.39)	ALOX15HSD17B10ECE1TET2TET3
	SCHEMBL5282303	0.86	MCL1 (0.45)	ALOX15HSD17B10MEN1KMT2A
	SCHEMBL2605612	0.84	SMN1; SMN2 (0.43)	ALOX15HSD17B10ECE1TET2ALDH1A1
	SCHEMBL5288745	0.83	CASP2 (0.47)	ALOX15MEN1KMT2A
	SCHEMBL16802900	0.83	ALOX15 (0.36)	ALOX15HSD17B10ECE1ALDH1A1SMN1; SMN2
	SCHEMBL11345101	0.82	ALOX15 (0.43)	ALOX15HSD17B10TET2TET3TET1
	SCHEMBL5177523	0.80	MCL1 (0.41)	ALOX15HSD17B10TET2TET3TET1
	SCHEMBL20165518	0.80	MEN1 (0.49)	ALDH1A1MEN1KMT2A
	SCHEMBL11234062	0.80	CASP2 (0.58)	MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.