Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 2/20 | 0.42 |
| ▸ | CCR3 | P51677 | 4/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544691 | 0.81 | KDM4E (0.47) | LMNASPRL3MBTL1PKM | |
| SCHEMBL7511921 | 0.81 | POLB (0.52) | SMN1; SMN2LMNAPOLBCCR3L3MBTL1 | |
| SCHEMBL6983413 | 0.80 | L3MBTL1 (0.62) | SMN1; SMN2L3MBTL1FAAHMEN1KMT2A | |
| SCHEMBL1004068 | 0.79 | SPR (0.53) | CA2SPRCCR3FAAHMEN1 | |
| SCHEMBL21651732 | 0.74 | LPL (0.44) | SMN1; SMN2LMNAPOLBL3MBTL1MEN1 | |
| SCHEMBL5239824 | 0.73 | EPHX2 (0.48) | L3MBTL1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL3994255 | 0.73 | POLB (0.56) | SMN1; SMN2GAALMNAPOLBOPRK1 | |
| SCHEMBL6186761 | 0.72 | L3MBTL1 (0.57) | SMN1; SMN2GAALMNACCR3L3MBTL1 | |
| SCHEMBL16256877 | 0.71 | LMNA (0.58) | SMN1; SMN2GAALMNAPOLBL3MBTL1 | |
| SCHEMBL725320 | 0.71 | LMNA (0.58) | SMN1; SMN2GAALMNAPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271619-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009126535-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-10-15 | — | — | WO | disclosed |