SCHEMBL1006687

SCHEMBL1006687

CCOC(=O)C1(C)OC2C=CC1C2

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
ALDH1A1 P00352 1/20 0.32
GLA P06280 1/20 0.32
ATM Q13315 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
BRD4 O60885 1/20 0.31
POLB P06746 1/20 0.30
ABCB11 O95342 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
SLC22A1 O15245 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
OPRM1 P35372 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20468466 0.72 ATM (0.32) MAPTATMMEN1KMT2APOLB
SCHEMBL20465367 0.71 SLC22A1 (0.32) ALDH1A1ATMMEN1KMT2APOLB
SCHEMBL7061157 0.70 ALDH1A1 (0.39) MAPTALDH1A1GLAATMMEN1
SCHEMBL13292181 0.69 BRD4 (0.33) MAPTALDH1A1GLAATMBRD4
SCHEMBL38663307 0.69 SMN1; SMN2 (0.32) ATMSLC22A1OPRM1SMN1; SMN2
SCHEMBL7175636 0.67 ALDH1A1 (0.36) MAPTALDH1A1GLAATMMEN1
SCHEMBL200228 0.67 CYP2C19 (0.40) BRD4POLBLMNAMAPK1SLC22A1
SCHEMBL16110306 0.66 OPRM1 (0.40) MAPTALDH1A1LMNAOPRM1SMN1; SMN2
SCHEMBL57714 0.66 TSHR (0.49) MAPTALDH1A1GLAMEN1KMT2A
SCHEMBL8945270 0.65 L3MBTL1 (0.34) MAPTALDH1A1GLAATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127520-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2018-05-10 US disclosed
US-9850325-B2 Method for producing ring-opening metathesis polymer hydride, and resin composition ZEON CORPORATION (JP) 2017-12-26 US disclosed
EP-2270063-B1 PROCESS FOR PRODUCING HYDROGENATED PRODUCT OF CYCLIC OLEFIN POLYMER PREPARED THROUGH RING-OPENING POLYMERIZATION ZEON CORP (JP) 2016-03-23 EP disclosed
US-20150051353-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2015-02-19 US disclosed
EP-2826802-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION Zeon Corporation (JP) 2015-01-21 EP disclosed
EP-1197509-B1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN ZEON CORP (JP) 2011-07-06 EP disclosed
EP-2270063-A2 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization NIPPON ZEON CO., LTD. (JP) 2011-01-05 EP disclosed
US-7084222-B2 Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst ZEON CORPORATION (JP) 2006-08-01 US disclosed
US-6908970-B2 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION (JP) 2005-06-21 US disclosed
US-20050014916-A1 Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst ZEON CORPORATION (JP) 2005-01-20 US disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014916-A1 Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst POR, CAD, HRH1 MAPT 2369/4885ALDH1A1 3138/4885GLA 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.