Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14364633 | 0.85 | CNR2 (0.32) | ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL14364640 | 0.80 | ALDH1A1 (0.32) | ELANEALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL14557992 | 0.77 | ELANE (0.34) | ELANEALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL10066812 | 0.77 | ALDH1A1 (0.35) | ELANEALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL13244482 | 0.74 | SIRT1 (0.32) | ELANEALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL14557892 | 0.74 | ELANE (0.34) | ELANEALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL13142202 | 0.73 | LMNA (0.35) | ELANEALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL13181448 | 0.72 | ELANE (0.33) | ELANEALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL14557906 | 0.72 | ELANE (0.33) | ELANEALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL10067130 | 0.71 | CASP1 (0.36) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178590-B2 | Block copolymer and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-15 | — | — | US | disclosed |