Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485582 | 0.80 | PAOX (0.39) | PAOXKDM4ESIGMAR1CA1CA2 | |
| SCHEMBL18803169 | 0.78 | PAOX (0.38) | PAOXKDM4ESIGMAR1CA1CA2 | |
| SCHEMBL3607141 | 0.74 | PAOX (0.42) | PAOXKDM4ECA1CA2CA9 | |
| SCHEMBL22015448 | 0.73 | ALOX15 (0.41) | PAOXCA1CA2CA9TP53 | |
| SCHEMBL14157926 | 0.73 | PAOX (0.35) | PAOXSIGMAR1CA1CA2CA9 | |
| SCHEMBL12015831 | 0.71 | PAOX (0.39) | PAOXSIGMAR1CA1CA2CA9 | |
| SCHEMBL13588746 | 0.71 | PAOX (0.36) | PAOXSIGMAR1CA1CA2CA9 | |
| SCHEMBL4564530 | 0.70 | PAOX (0.47) | PAOXSIGMAR1ALDH1A1 | |
| SCHEMBL17102198 | 0.70 | CA2 (0.40) | PAOXSIGMAR1CA1CA2CA9 | |
| SCHEMBL17850520 | 0.70 | PAOX (0.38) | PAOXSIGMAR1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121771-B2 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2016-12-07 | — | — | EP | disclosed |
| US-8338499-B2 | Amine co-initiators for radiation curable compositions | AGFA GRAPHICS NV (BE) | 2012-12-25 | — | — | US | disclosed |
| EP-2121771-B1 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2012-06-27 | — | — | EP | disclosed |
| US-20100041784-A1 | NOVEL RADIATION CURABLE COMPOSITIONS | AGFA GRAPHICS NV (BE) | 2010-02-18 | — | — | US | disclosed |