Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844752 | 0.90 | HTT (0.64) | HTTSGMS2NPC1MEN1KMT2A | |
| SCHEMBL5689805 | 0.90 | HTT (0.57) | HTTSGMS2NPC1MEN1KMT2A | |
| SCHEMBL16908814 | 0.89 | CYP3A4 (0.56) | HTTSGMS2NPC1MEN1KMT2A | |
| SCHEMBL8025089 | 0.86 | HTT (0.59) | HTTSGMS2NPC1MEN1KMT2A | |
| SCHEMBL4415350 | 0.85 | HTT (0.75) | HTTSGMS2NPC1MEN1KMT2A | |
| SCHEMBL9574717 | 0.83 | HTT (0.73) | HTTSGMS2NPC1MEN1KMT2A | |
| SCHEMBL978857 | 0.83 | HTT (0.64) | HTTSGMS2NPC1MEN1KMT2A | |
| SCHEMBL112903 | 0.82 | SGMS2 (0.66) | HTTSGMS2NPC1KMT2AGAA | |
| SCHEMBL29433417 | 0.82 | SGMS2 (0.66) | HTTSGMS2NPC1KMT2AGAA | |
| SCHEMBL9696207 | 0.82 | SGMS2 (0.66) | HTTSGMS2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723191-B1 | LIQUID CRYSTAL POLYCARBONATES AND METHODS OF PREPARING SAME | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2015-07-22 | — | — | EP | claimed |
| US-8865833-B2 | Polycarbonate composition comprising nanomaterials | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2014-10-21 | — | — | US | claimed |
| US-7666977-B2 | Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-02-23 | — | — | US | claimed |
| EP-1577333-B1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP (NL) | 2008-12-03 | — | — | EP | claimed |
| WO-2008136841-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-11-13 | — | — | WO | claimed |
| US-20080275209-A1 | POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS | GENERAL ELECTRIC COMPANY (US) | 2008-11-06 | — | — | US | claimed |
| EP-1504048-B1 | METHOD OF PREPARING POLYESTERCARBONATES | GEN ELECTRIC (US) | 2007-11-21 | — | — | EP | claimed |
| US-7211641-B2 | high heat resistance, outstanding dimensional stability and excellent solvent resistance | GENERAL ELECTRIC COMPANY (US) | 2007-05-01 | — | — | US | claimed |
| EP-1723191-A1 | LIQUID CRYSTAL POLYCARBONATES AND METHODS OF PREPARING SAME | GENERAL ELECTRIC COMPANY (US) | 2006-11-22 | — | — | EP | claimed |
| EP-1414888-B1 | EXTRUSION METHOD FOR MAKING POLYCARBONATE | GEN ELECTRIC (US) | 2006-05-31 | — | — | EP | claimed |
| WO-2004033531-A1 | METHOD AND APPARATUS TO MAKE HIGH MOLECULAR WEIGHT MELT POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2004-04-22 | — | — | WO | claimed |
| US-20040068086-A1 | Method and apparatus to make high molecular weight melt polycarbonate | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2004-04-08 | — | — | US | claimed |
| WO-2003096330-A1 | METHOD OF ENHANCING PIT REPLICATION IN OPTICAL DISKS | GENERAL ELECTRIC COMPANY (US) | 2003-11-20 | — | — | WO | claimed |
| US-20030212241-A1 | Method of enhancing pit replication in optical disks | GENERAL ELECTRIC COMPANY | 2003-11-13 | — | — | US | claimed |
| WO-2003087190-A1 | METHOD OF PREPARING POLYESTERCARBONATES | GENERAL ELECTRIC COMPANY (US) | 2003-10-23 | — | — | WO | claimed |
| US-6600004-B1 | Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic | GENERAL ELECTRIC COMPANY | 2003-07-29 | — | — | US | claimed |
| US-20030120025-A1 | Process for the production of polycarbonate | GENERAL ELECTRIC COMPANY | 2003-06-26 | — | — | US | claimed |
| US-6525163-B1 | Reducing static charge, improving heat aging, and lowering water absorption by increasing endcap levels | GENERAL ELECTRIC COMPANY | 2003-02-25 | — | — | US | claimed |
| WO-2003010220-A1 | EXTRUSION METHOD FOR MAKING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | claimed |
| US-6506871-B1 | Ester interchange of bis(methyl salicyl) carbonate and bisphenol A in presence of tetrabutylphosphonium acetate catalyst | GENERAL ELECTRIC COMPANY | 2003-01-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120025-A1 | Process for the production of polycarbonate | RNGTT, CAPG, RPL30 | HTT 2326/4885SGMS2 1431/4885NPC1 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.