Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006768 | 0.90 | HTT (0.64) | HTTSGMS2KMT2AMEN1NPC1 | |
| SCHEMBL9574658 | 0.85 | HSD17B10 (0.60) | HTTSGMS2KMT2AMEN1NPC1 | |
| SCHEMBL4343858 | 0.84 | ESR1 (0.51) | HTTKMT2AMEN1NPSR1GAA | |
| SCHEMBL2844752 | 0.83 | HTT (0.64) | HTTSGMS2KMT2AMEN1NPC1 | |
| Bicarbonate SCHEMBL7114860 | 0.83 | ESR1 (0.50) | KMT2AMEN1SMN1; SMN2NPSR1GAA | |
| SCHEMBL5155893 | 0.82 | ALDH1A1 (0.50) | KMT2AMEN1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL4335276 | 0.81 | ALDH1A1 (0.45) | HTTKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL5157734 | 0.81 | MEN1 (0.51) | KMT2AMEN1NPSR1ALDH1A1TSHR | |
| SCHEMBL5689370 | 0.80 | CTNNB1 (0.57) | HTTKMT2AMEN1SMN1; SMN2NPSR1 | |
| SCHEMBL16908814 | 0.80 | CYP3A4 (0.56) | HTTSGMS2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348003-B1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GEN ELECTRIC (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1427770-B1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GEN ELECTRIC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1427770-A1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| EP-1348003-A1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-10-01 | — | — | EP | disclosed |
| US-20030120025-A1 | Process for the production of polycarbonate | GENERAL ELECTRIC COMPANY | 2003-06-26 | — | — | US | disclosed |
| WO-2003022905-A1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-03-20 | — | — | WO | disclosed |
| US-6525163-B1 | Reducing static charge, improving heat aging, and lowering water absorption by increasing endcap levels | GENERAL ELECTRIC COMPANY | 2003-02-25 | — | — | US | disclosed |
| US-20020128425-A1 | Process for the production of polycarbonate | GENERAL ELECTRIC COMPANY | 2002-09-12 | — | — | US | disclosed |
| WO-2002060977-A1 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2002-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120025-A1 | Process for the production of polycarbonate | RNGTT, CAPG, RPL30 | HTT 2326/4885SGMS2 1431/4885KMT2A 3611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.