Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844752 | 0.86 | HTT (0.64) | HTTSGMS2PTGER1NPC1MEN1 | |
| SCHEMBL1006768 | 0.86 | HTT (0.64) | HTTSGMS2PTGER1NPC1MEN1 | |
| SCHEMBL8587610 | 0.84 | HCRTR1 (0.57) | HTTMEN1KMT2ANPSR1GAA | |
| SCHEMBL340937 | 0.83 | HTT (0.69) | HTTSGMS2PTGER1NPC1MEN1 | |
| SCHEMBL978857 | 0.83 | HTT (0.64) | HTTSGMS2PTGER1NPC1MEN1 | |
| SCHEMBL4431127 | 0.83 | SGMS2 (0.59) | HTTSGMS2PTGER1NPC1MEN1 | |
| SCHEMBL16908814 | 0.82 | CYP3A4 (0.56) | HTTSGMS2PTGER1NPC1MEN1 | |
| SCHEMBL28213609 | 0.81 | ADRB2 (0.52) | HTTNPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4415350 | 0.81 | HTT (0.75) | HTTSGMS2PTGER1NPC1MEN1 | |
| SCHEMBL28373054 | 0.81 | HCRTR1 (0.50) | HTTMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980239-A1 | COSMETIC SKIN CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998051659-A1 | SALICYLOXY α-CARBOXY ACIDS AND PREPARATION THEREOF | UNILEVER PLC (GB) | 1998-11-19 | — | — | WO | disclosed |
| WO-1998051274-A1 | COSMETIC SKIN CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 1998-11-19 | — | — | WO | disclosed |
| US-5762947-A | CONTROLLING OILY SKIN | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1998-06-09 | — | — | US | disclosed |