Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENTPD5 | O75356 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.44 |
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060577 | 0.72 | ENTPD5 (0.40) | ENTPD5OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL10899122 | 0.69 | RARB (0.50) | ENTPD5OPRM1OPRD1OPRK1 | |
| SCHEMBL11167948 | 0.68 | OPRM1 (0.43) | OPRM1OPRD1OPRK1SIGMAR1MRGPRX2 | |
| SCHEMBL13424483 | 0.66 | OPRM1 (0.47) | ENTPD5OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL12442825 | 0.66 | OPRM1 (0.47) | ENTPD5OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL6248845 | 0.65 | PDE4D (0.42) | ENTPD5OPRM1 | |
| SCHEMBL1360287 | 0.65 | RXRA (0.49) | — | |
| SCHEMBL7211111 | 0.65 | CYP3A4 (0.44) | OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL29911088 | 0.65 | CYP3A4 (0.44) | OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL30701838 | 0.65 | RXRA (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2418191-A1 | Long-chain trimethoxyphenylalkanol derivatives, and pharmaceuticals comprising the same | Meiji Co., Ltd. (JP) | 2012-02-15 | — | — | EP | disclosed |