SCHEMBL11167948

SCHEMBL11167948

CC1C(C)(C)c2ccc(O)cc2C1(C)C

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 14/20 0.43
OPRD1 P41143 8/20 0.42
OPRK1 P41145 8/20 0.42
MRGPRX2 Q96LB1 2/20 0.40
SIGMAR1 Q99720 3/20 0.38
RXRA P19793 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1468020 0.76 RXRA (0.39) RXRA
SCHEMBL29870908 0.76 RXRA (0.39) RXRA
SCHEMBL10643510 0.74 ESR1 (0.56) RXRA
SCHEMBL10335841 0.74 ADRA2A (0.35) SIGMAR1RXRA
SCHEMBL10963336 0.72 POLB (0.36) RXRA
SCHEMBL9869229 0.71 RXRA (0.38) RXRA
SCHEMBL10705439 0.71 TRPA1 (0.38) RXRA
SCHEMBL20610680 0.71 LMNA (0.36) RXRA
SCHEMBL6435749 0.71 HTR2A (0.37) SIGMAR1RXRA
SCHEMBL29431859 0.71 HTR2A (0.37) SIGMAR1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4370505-A 1,1,3,3-Substituted hydroxyindanes BAYER AKTIENGESELLSCHAFT (DE) 1983-01-25 US claimed
WO-2023166424-A1 COPOLYMERS DERIVED FROM DICYCLOPENTADIENE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-09-07 WO disclosed
WO-2023073614-A1 COPOLYMERS DERIVED FROM DICYCLOPENTADIENE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-04 WO disclosed
WO-2023073558-A1 COPOLYMER FOR CROSS-LINKABLE NETWORKS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-04 WO disclosed
US-4370505-A 1,1,3,3-Substituted hydroxyindanes BAYER AKTIENGESELLSCHAFT (DE) 1983-01-25 US disclosed
US-3954889-A Process for the production of 1,1,3,3-substituted hydroxyindanes BAYER AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed