Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1006782

C(c1ccccc1)=[Ru+2](=c1n(C2CCCCC2)ccn1C1CCCCC1)=c1n(C2CCCCC2)ccn1C1CCCCC1.[Cl-].[Cl-]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.35
KDM4E B2RXH2 2/20 0.33
IL4I1 Q96RQ9 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
ALDH1A1 P00352 3/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 2/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1172655 0.78 KDM4E (0.34) SLC18A3KDM4EIL4I1POLBGAA
Hydrochloric Acid SCHEMBL1006742 0.76 HSD11B1 (0.39) SLC18A3KDM4EPOLBGAAALDH1A1
SCHEMBL4607064 0.70 SLC18A3 (0.36) SLC18A3KDM4EIL4I1POLBGAA
Hydrochloric Acid SCHEMBL1008609 0.69 SLC18A3 (0.35) SLC18A3KDM4EIL4I1POLBGAA
SCHEMBL819175 0.68 IL4I1 (0.34) SLC18A3KDM4EIL4I1POLBGAA
Hydrochloric Acid SCHEMBL1007345 0.67 SLC18A3 (0.31) SLC18A3KDM4EIL4I1
SCHEMBL2144270 0.67 SLC18A3 (0.33) SLC18A3KDM4EIL4I1POLBGAA
SCHEMBL1172657 0.66 SLC18A3 (0.33) SLC18A3KDM4EIL4I1POLBGAA
Hydrochloric Acid SCHEMBL3842277 0.66 SLC18A3 (0.33) SLC18A3KDM4EIL4I1POLBGAA
SCHEMBL7190295 0.64 ALDH1A1 (0.42) SLC18A3KDM4EALDH1A1NPSR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3159365-B1 CYCLOPENTENE RING-OPENING POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, AND POLYMER CROSSLINKED PRODUCT ZEON CORP (JP) 2025-01-22 EP disclosed
US-11535696-B2 Crosslinkable composition and crosslinked product ZEON CORPORATION (JP) 2022-12-27 US disclosed
US-20220380522-A1 RING-OPENED COPOLYMER ZEON CORPORATION (JP) 2022-12-01 US disclosed
EP-4079781-A1 RING-OPENED COPOLYMER Zeon Corporation (JP) 2022-10-26 EP disclosed
EP-3533829-B1 RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2021-11-24 EP disclosed
EP-3689938-A1 LIQUID COPOLYMER FORMED BY RING-OPENING COPOLYMERIZATION OF CYCLOPENTENE, CROSSLINKABLE COMPOSITION, AND CROSSLINKED RUBBER OBJECT Zeon Corporation (JP) 2020-08-05 EP disclosed
US-20200055975-A1 CROSSLINKABLE COMPOSITION AND CROSSLINKED PRODUCT ZEON CORPORATION (JP) 2020-02-20 US disclosed
EP-3533832-A1 CROSSLINKABLE COMPOSITION AND CROSSLINKED PRODUCT Zeon Corporation (JP) 2019-09-04 EP disclosed
EP-3533829-A1 RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT Zeon Corporation (JP) 2019-09-04 EP disclosed
US-10400060-B2 Cyclopentene ring-opening polymer and method of production of same, polymer composition, and cross-linked polymer ZEON CORPORATION (JP) 2019-09-03 US disclosed
US-20060040201-A1 Radiation sensitive resin composition ZEON CORPORATION (JP) 2006-02-23 US disclosed
EP-1275675-B1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE ZEON CORP (JP) 2005-12-07 EP disclosed
US-6908970-B2 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION (JP) 2005-06-21 US disclosed
US-6815516-B2 HEAT RESISTANCE, SOLVENT SOLUBILITY ZEON CORPORATION (JP) 2004-11-09 US disclosed
EP-1408064-A1 OPEN-RING COPOLYMER, HYDROGENATED OPEN-RING COPOLYMER, PROCESSES FOR PRODUCTION OF BOTH, AND COMPOSITIONS Zeon Corporation (JP) 2004-04-14 EP disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-20030018138-A1 Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these ZEON CORPORATION (JP) 2003-01-23 US disclosed
EP-1275675-A1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE Zeon Corporation (JP) 2003-01-15 EP disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed