Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068720 | 0.87 | BRD4 (0.53) | ADRB1ADRB3ADRB2BRD4CREBBP | |
| SCHEMBL10068778 | 0.85 | HPGD (0.43) | ADRB1ADRB3ADRB2BRD4CREBBP | |
| SCHEMBL10068557 | 0.85 | BRD4 (0.42) | ADRB1ADRB3ADRB2BRD4CREBBP | |
| SCHEMBL10069315 | 0.84 | ADRB1 (0.43) | ADRB1ADRB3ADRB2BRD4CREBBP | |
| SCHEMBL10068770 | 0.84 | FAAH (0.44) | ADRB1ADRB3ADRB2BRD4CREBBP | |
| SCHEMBL10068957 | 0.84 | HPGD (0.42) | ADRB1ADRB3ADRB2BRD4CREBBP | |
| SCHEMBL10069563 | 0.83 | ADRB2 (0.47) | ADRB1ADRB3ADRB2MEN1MAPT | |
| SCHEMBL10068568 | 0.82 | SMN1; SMN2 (0.45) | ADRB1ADRB3ADRB2BRD4CREBBP | |
| SCHEMBL10068804 | 0.82 | F2 (0.43) | ADRB1ADRB3ADRB2BRD4CREBBP | |
| SCHEMBL10068545 | 0.81 | ADRB2 (0.37) | ADRB1ADRB3ADRB2MRGPRX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958912-B | Benzohydrol derivatives, a preparation process and pharmaceutical use thereof | SHANGHAI HENGRUI PHARM CO LTD | 2015-01-14 | — | — | CN | disclosed |
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |