Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068770 | 0.90 | FAAH (0.44) | BRD4CREBBPADRB1ADRB3ADRB2 | |
| SCHEMBL10068557 | 0.89 | BRD4 (0.42) | BRD4CREBBPADRB1ADRB3ADRB2 | |
| SCHEMBL10068778 | 0.89 | HPGD (0.43) | BRD4CREBBPADRB1ADRB3ADRB2 | |
| SCHEMBL10069315 | 0.88 | ADRB1 (0.43) | BRD4CREBBPADRB1ADRB3ADRB2 | |
| SCHEMBL10068957 | 0.88 | HPGD (0.42) | BRD4CREBBPADRB1ADRB3ADRB2 | |
| SCHEMBL10068544 | 0.87 | ADRB1 (0.43) | BRD4CREBBPADRB1ADRB3ADRB2 | |
| SCHEMBL10069563 | 0.86 | ADRB2 (0.47) | ADRB1ADRB3ADRB2ALDH1A1MAPT | |
| SCHEMBL10068804 | 0.86 | F2 (0.43) | BRD4CREBBPADRB1ADRB3ADRB2 | |
| SCHEMBL10068568 | 0.84 | SMN1; SMN2 (0.45) | BRD4CREBBPADRB1ADRB3ADRB2 | |
| SCHEMBL10068540 | 0.83 | ADRB3 (0.45) | ADRB1ADRB3ADRB2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958912-B | Benzohydrol derivatives, a preparation process and pharmaceutical use thereof | SHANGHAI HENGRUI PHARM CO LTD | 2015-01-14 | — | — | CN | disclosed |
| CN-102372653-A | Diphenyl methanol derivative, preparation method thereof and application of diphenyl methanol derivative in medicine | JIANGSU HENGRUI MEDICINE CO | 2012-03-14 | — | — | CN | disclosed |
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |