Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10068720 | 0.86 | BRD4 (0.53) | BRD4CREBBPADRB2ADRB1ADRB3 | |
| SCHEMBL10068778 | 0.84 | HPGD (0.43) | BRD4CREBBPADRB2ADRB1ADRB3 | |
| SCHEMBL10068557 | 0.84 | BRD4 (0.42) | BRD4CREBBPADRB2ADRB1ADRB3 | |
| SCHEMBL10069315 | 0.83 | ADRB1 (0.43) | BRD4CREBBPADRB2ADRB1ADRB3 | |
| SCHEMBL10068770 | 0.83 | FAAH (0.44) | BRD4CREBBPADRB2ADRB1ADRB3 | |
| SCHEMBL10068957 | 0.83 | HPGD (0.42) | BRD4CREBBPFFAR1ADRB2ADRB1 | |
| SCHEMBL10068544 | 0.82 | ADRB1 (0.43) | BRD4CREBBPADRB2ADRB1ADRB3 | |
| SCHEMBL10069563 | 0.82 | ADRB2 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL10068801 | 0.81 | REN (0.41) | F2FFAR1CNR2 | |
| SCHEMBL10069336 | 0.79 | SLC6A3 (0.43) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958912-B | Benzohydrol derivatives, a preparation process and pharmaceutical use thereof | SHANGHAI HENGRUI PHARM CO LTD | 2015-01-14 | — | — | CN | disclosed |
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |