Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSH | P09668 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499190 | 0.83 | CTSK (0.40) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL499191 | 0.83 | CTSK (0.40) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL3338713 | 0.73 | GPR88 (0.41) | CTSKCTSLCTSBDPP4GPR88 | |
| SCHEMBL3607510 | 0.73 | GPR88 (0.41) | CTSKCTSLCTSBDPP4GPR88 | |
| SCHEMBL3338710 | 0.73 | GPR88 (0.41) | CTSKCTSLCTSBDPP4GPR88 | |
| SCHEMBL172946 | 0.71 | SIGMAR1 (0.38) | CTSKCTSLCTSBCTSHSIGMAR1 | |
| SCHEMBL173045 | 0.71 | SIGMAR1 (0.38) | CTSKCTSLCTSBCTSHSIGMAR1 | |
| SCHEMBL12632063 | 0.71 | CTSS (0.34) | CTSKCTSSGPR88 | |
| SCHEMBL3588546 | 0.71 | ANPEP (0.40) | CTSKCTSLCTSBDPP4GPR88 | |
| SCHEMBL3588545 | 0.71 | ANPEP (0.40) | CTSKCTSLCTSBDPP4GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |