Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CASP1 | P29466 | 4/20 | 0.35 |
| ▸ | CASP7 | P55210 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069628 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL10069590 | 0.85 | ALDH1A1 (0.39) | ERCC5FEN1ERCC1ERCC4ALDH1A1 | |
| SCHEMBL10069615 | 0.84 | ERCC5 (0.39) | ERCC5FEN1ERCC1ERCC4ALDH1A1 | |
| SCHEMBL10069594 | 0.80 | MAPT (0.38) | ERCC5FEN1ERCC1ERCC4ALDH1A1 | |
| SCHEMBL10069601 | 0.80 | ALDH1A1 (0.36) | ERCC5FEN1ALDH1A1CYP1A2CASP1 | |
| SCHEMBL10069595 | 0.80 | ALDH1A1 (0.38) | ERCC5FEN1ERCC1ERCC4ALDH1A1 | |
| SCHEMBL10069616 | 0.79 | ALDH1A1 (0.36) | ERCC5FEN1ALDH1A1CASP1HSD17B10 | |
| SCHEMBL10069591 | 0.79 | ESR1 (0.35) | ERCC5FEN1ERCC1ERCC4ALDH1A1 | |
| SCHEMBL10069620 | 0.78 | MAPK1 (0.36) | ERCC5FEN1ERCC1ERCC4ALDH1A1 | |
| SCHEMBL10069606 | 0.78 | ALDH1A1 (0.37) | ERCC5FEN1ALDH1A1POLBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047993-A2 | N-HYDROXYPYRIMIDINE-2,4-DIONES AS INHIBITORS OF HIV AND HCV | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-04-12 | — | — | WO | disclosed |