Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070944 | 0.91 | MMP9 (0.34) | THRATHRBMMP9MMP2CYP19A1 | |
| SCHEMBL10070392 | 0.81 | TLR7 (0.30) | — | |
| SCHEMBL12894144 | 0.74 | MAPT (0.36) | KDM4E | |
| SCHEMBL15101373 | 0.73 | MET (0.30) | — | |
| SCHEMBL10069877 | 0.71 | THRA (0.34) | THRATHRBCNR2LMNA | |
| SCHEMBL10071002 | 0.70 | TSHR (0.36) | THRATHRBCNR2LMNAKDM4E | |
| SCHEMBL12894051 | 0.69 | MAPT (0.39) | THRATHRBLMNAKDM4E | |
| SCHEMBL10070414 | 0.69 | CNR2 (0.39) | CNR2 | |
| SCHEMBL12140417 | 0.67 | MAPT (0.39) | THRBLMNAKDM4E | |
| SCHEMBL10071008 | 0.66 | ALDH1A1 (0.33) | MMP9MMP1MMP13ADAM17LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006680-A1 | 7, 9-NITROGEN RADICAL-4-OXO-4H-PYRIDO[L,2-A]PYRIMIDINE-2-CARBOXYLIC ACID BENZYLAMIDE ANTI-VIRALS | AVEXA LIMITED (AU) | 2012-01-19 | — | — | WO | disclosed |