Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122796 | 0.95 | ALDH1A1 (0.44) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL10071724 | 0.90 | CA1 (0.42) | HPGDALDH1A1GAASIGMAR1EPHX1 | |
| SCHEMBL22402873 | 0.88 | TDP1 (0.47) | HPGDMAPTTDP1CA1CA2 | |
| SCHEMBL3474501 | 0.88 | TDP1 (0.47) | HPGDMAPTTDP1CA1CA2 | |
| SCHEMBL3402806 | 0.87 | TDP1 (0.47) | ALDH1A1GAASIGMAR1TDP1CA1 | |
| SCHEMBL18946793 | 0.86 | ALDH1A1 (0.40) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL17468120 | 0.86 | TDP1 (0.49) | ALDH1A1GAATDP1CA1CA2 | |
| SCHEMBL5555779 | 0.85 | CA1 (0.39) | HPGDGAASIGMAR1TDP1CA1 | |
| SCHEMBL17381378 | 0.85 | TDP1 (0.51) | GAATDP1CA1CA2MEN1 | |
| SCHEMBL337313 | 0.85 | TDP1 (0.51) | GAATDP1CA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080608-B1 | MASS LABELS | ELECTROPHORETICS LTD (GB) | 2023-02-01 | — | — | EP | disclosed |
| US-10697976-B2 | Mass labels | ELECTROPHORETICS LIMITED (GB) | 2020-06-30 | — | — | US | disclosed |
| US-20170045526-A1 | MASS LABELS | ELECTROPHORETICS LIMITED (GB) | 2017-02-16 | — | — | US | disclosed |
| US-20170045526-A1 | MASS LABELS | ELECTROPHORETICS LIMITED (GB) | 2017-02-16 | — | — | US | disclosed |
| US-20120165275-A1 | Nitrogen-Based Linkers for Attaching Modifying Groups to Polypeptides and Other Macromolecules | AFFYMAX, INC. (US) | 2012-06-28 | — | — | US | disclosed |
| US-8106154-B2 | Nitrogen-based linkers for attaching modifying groups to polypeptides and other macromolecules | AFFYMAX, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20090048147-A1 | NITROGEN-BASED LINKERS FOR ATTACHING MODIFYING GROUPS TO POLYPEPTIDES AND OTHER MACROMOLECULES | AFFYMAX, INC. (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165275-A1 | Nitrogen-Based Linkers for Attaching Modifying Groups to Polypeptides and Other Macromolecules | DNPEP, NGLY1, LNPEP | KDM4E 3293/4885HPGD 921/4885ALDH1A1 4660/4885 |
| US-20090048147-A1 | NITROGEN-BASED LINKERS FOR ATTACHING MODIFYING GROUPS TO POLYPEPTIDES AND OTHER MACROMOLECULES | NGLY1, YWHAZ, HBZ | KDM4E 1348/4885HPGD 2325/4885ALDH1A1 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.