Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.88 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.73 |
| ▸ | BCHE | P06276 | 1/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197262 | 0.93 | PTGS2 (0.77) | ACHEMEN1KMT2AHDAC3HDAC6 | |
| SCHEMBL16414873 | 0.93 | PTGS2 (0.77) | ACHEMEN1KMT2AHDAC3HDAC6 | |
| N-Feruloyl Serotonin SCHEMBL12063415 | 0.92 | PTGS2 (0.79) | ACHEMEN1KMT2AHDAC3HDAC6 | |
| N-Feruloyl Serotonin SCHEMBL1809357 | 0.92 | PTGS2 (0.79) | ACHEMEN1KMT2AHDAC3HDAC6 | |
| N-Feruloyl Serotonin SCHEMBL30037765 | 0.92 | PTGS2 (0.79) | ACHEMEN1KMT2AHDAC3HDAC6 | |
| SCHEMBL18122175 | 0.90 | ACHE (0.81) | ACHEMEN1KMT2AHDAC3HDAC6 | |
| SCHEMBL10070987 | 0.90 | ACHE (0.88) | ACHEMEN1KMT2ABCHEPTGS2 | |
| SCHEMBL4434094 | 0.90 | ACHE (0.88) | ACHEMEN1KMT2ABCHEPTGS2 | |
| SCHEMBL31634290 | 0.90 | ACHE (0.88) | ACHEMEN1KMT2ABCHEPTGS2 | |
| SCHEMBL798053 | 0.89 | HDAC3 (0.81) | ACHEMEN1KMT2AHDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | AJINOMOTO CO. INC (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140255327-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | ACHE 291/4885MEN1 4229/4885KMT2A 644/4885 |
| US-20120070395-A1 | NOVEL AMIDE DERIVATIVE AND WHITENING AGENT | CUTA, NAT1, TYR | ACHE 291/4885MEN1 4229/4885KMT2A 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.