SCHEMBL798053

SCHEMBL798053

COc1ccc2[nH]cc(CCNC(=O)/C=C/c3ccc(O)cc3)c2c1

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.81
HDAC6 Q9UBN7 3/20 0.81
MAOB P27338 1/20 0.79
ACHE P22303 4/20 0.70
HDAC4 P56524 1/20 0.69
HDAC1 Q13547 1/20 0.69
HDAC7 Q8WUI4 1/20 0.69
HDAC2 Q92769 1/20 0.69
HDAC10 Q969S8 1/20 0.69
HDAC11 Q96DB2 1/20 0.69
HDAC8 Q9BY41 1/20 0.69
HDAC9 Q9UKV0 1/20 0.69
HDAC5 Q9UQL6 1/20 0.69
BCHE P06276 3/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
PTGS2 P35354 1/20 0.67
MTNR1A P48039 3/20 0.66
MTNR1B P49286 2/20 0.65
KDM4E B2RXH2 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL798054 1.00 HDAC3 (0.81) HDAC3HDAC6MAOBACHEHDAC4
N-P-Methoxy Cinnamoyl Serotonin SCHEMBL10071700 0.94 MAOB (0.82) HDAC3HDAC6MAOBACHEHDAC4
SCHEMBL28924828 0.91 HDAC3 (0.79) HDAC3HDAC6MAOBACHEHDAC4
SCHEMBL28924825 0.91 HDAC3 (0.79) HDAC3HDAC6MAOBACHEHDAC4
SCHEMBL28924880 0.91 HDAC3 (0.79) HDAC3HDAC6ACHEHDAC4HDAC1
SCHEMBL28924879 0.91 HDAC3 (0.79) HDAC3HDAC6ACHEHDAC4HDAC1
SCHEMBL16414873 0.90 PTGS2 (0.77) HDAC3HDAC6MAOBACHEHDAC4
SCHEMBL14197262 0.90 PTGS2 (0.77) HDAC3HDAC6MAOBACHEHDAC4
SCHEMBL16710735 0.89 HDAC3 (0.66) HDAC3HDAC6MAOBACHEHDAC4
SCHEMBL10071694 0.89 ACHE (0.88) HDAC3HDAC6MAOBACHEHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122048813-A Cloth skip stitch detection method 星智元(厦门)科技有限公司 2026-05-15 CN disclosed
EP-3548510-B1 COMPOUNDS USEFUL FOR THE TREATMENT AND/OR CARE OF THE SKIN, HAIR, NAILS AND/OR MUCOUS MEMBRANES LUBRIZOL ADVANCED MAT INC (US) 2024-10-02 EP disclosed
EP-4389136-A1 NEUROCOSMETIC COMPOSITION FOR PREVENTING THE EFFECTS OF STRESS C.F.E.B. Sisley (FR) 2024-06-26 EP disclosed
US-20220265543-A1 COSMETIC COMPOSITIONS AND USES THEREOF ALUMIER LABS, INC. (CA) 2022-08-25 US disclosed
CN-114728486-A Multilayer pipe and method for producing same 美国圣戈班性能塑料公司 2022-07-08 CN disclosed
EP-4003274-A1 COSMETIC COMPOSITIONS COMPRISING PLANT EXTRACTS AND USES THEREOF Alumier Europe Limited (MT) 2022-06-01 EP disclosed
EP-2790659-B1 COSMETIC COMPOSITION FOR STIMULATING THE CELLULAR ANTI-AGING FUNCTIONS OF THE SKIN SYNTIVIA (FR) 2017-03-01 EP disclosed
EP-2616439-B1 TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY COUNCIL SCIENT IND RES (IN) 2015-12-16 EP disclosed
US-20150031740-A1 COSMETIC COMPOSITION FOR STIMULATING THE CELLULAR ANTI-AGING FUNCTIONS OF THE SKIN UNIVERSITE PAUL SABATIER TOULOUSE III (FR) 2015-01-29 US disclosed
US-20150031740-A1 COSMETIC COMPOSITION FOR STIMULATING THE CELLULAR ANTI-AGING FUNCTIONS OF THE SKIN UNIVERSITE PAUL SABATIER TOULOUSE III (FR) 2015-01-29 US disclosed
US-8901317-B2 Tryptamine derivatives, their preparation and their use in gastropathy COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-12-02 US disclosed
US-8901317-B2 Tryptamine derivatives, their preparation and their use in gastropathy COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-12-02 US disclosed
US-20130197052-A1 TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY UNIVERSITY OF CALCUTTA (IN) 2013-08-01 US disclosed
US-20130197052-A1 TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY UNIVERSITY OF CALCUTTA (IN) 2013-08-01 US disclosed
EP-2616439-A1 TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY Council of Scientific & Industrial Research (IN) 2013-07-24 EP disclosed
WO-2013087834-A2 COSMETIC COMPOSITION FOR STIMULATING THE CELLULAR ANTI-AGING FUNCTIONS OF THE SKIN SYNTIVIA (FR) 2013-06-20 WO disclosed
WO-2012035406-A1 TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-03-22 WO disclosed
WO-2012035406-A1 TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-03-22 WO disclosed
US-20120070395-A1 NOVEL AMIDE DERIVATIVE AND WHITENING AGENT AJINOMOTO CO. INC (JP) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220265543-A1 COSMETIC COMPOSITIONS AND USES THEREOF CUTA, CERS2, GLA HDAC3 1367/4885HDAC6 825/4885MAOB 1077/4885
US-20150031740-A1 COSMETIC COMPOSITION FOR STIMULATING THE CELLULAR ANTI-AGING FUNCTIONS OF THE SKIN H1-0, C1R, H1-3 HDAC3 793/4885HDAC6 1520/4885MAOB 972/4885
US-20120070395-A1 NOVEL AMIDE DERIVATIVE AND WHITENING AGENT CUTA, NAT1, TYR HDAC3 390/4885HDAC6 218/4885MAOB 416/4885
US-20130197052-A1 TRYPTAMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN GASTROPATHY HTRA2, AIFM1, SI HDAC3 1237/4885HDAC6 2438/4885MAOB 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.