Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | VDR | P11473 | 5/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | ALPG | P10696 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16253381 | 0.87 | MAPT (0.68) | MAPTAPPVDRMEN1LMNA | |
| SCHEMBL8995923 | 0.87 | MAPT (0.68) | MAPTAPPVDRMEN1LMNA | |
| Hydrochloric Acid SCHEMBL29429013 | 0.86 | MAPT (0.67) | MAPTAPPVDRMEN1LMNA | |
| Iodide SCHEMBL29249905 | 0.86 | MAPT (0.70) | MAPTAPPVDRMEN1LMNA | |
| Hydrochloric Acid SCHEMBL14674430 | 0.86 | MAPT (0.67) | MAPTAPPVDRMEN1LMNA | |
| Hydrochloric Acid SCHEMBL14675272 | 0.86 | MAPT (0.67) | MAPTAPPVDRMEN1LMNA | |
| Iodide SCHEMBL28888918 | 0.85 | MAPT (0.54) | MAPTAPPVDRATG4BMEN1 | |
| Iodide SCHEMBL28888917 | 0.85 | MAPT (0.54) | MAPTAPPVDRATG4BMEN1 | |
| SCHEMBL14159484 | 0.85 | MAPT (0.58) | MAPTAPPVDRMEN1LMNA | |
| SCHEMBL10039846 | 0.83 | MAPT (0.49) | MAPTAPPVDRMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9849196-B2 | Methods and compositions for altering photophysical properties of fluorophores via proximal quenching | CORNELL UNIVERSITY (US) | 2017-12-26 | — | — | US | disclosed |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2015-11-19 | — | — | US | disclosed |
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | CORNELL UNIVERSITY (US) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027689-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERITES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, PPOX, PRDX5 | MAPT 2134/4885APP 2507/4885VDR 2764/4885 |
| US-20150328340-A1 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING | APEX1, ARFGEF1, PRDX3 | MAPT 2005/4885APP 2466/4885VDR 2798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.