Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055923 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1MAPTL3MBTL1CYP1A2 | |
| SCHEMBL1002665 | 0.81 | GABRA1 (0.61) | KDM4EALDH1A1MAPTTDP1LMNA | |
| SCHEMBL7125837 | 0.80 | CYP2A6 (0.44) | KDM4EALDH1A1MAPTTDP1LMNA | |
| SCHEMBL4746752 | 0.80 | CYP2A6 (0.38) | KDM4EALDH1A1MAPTTDP1LMNA | |
| SCHEMBL12660191 | 0.79 | AKR1C3 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10490689 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1MAPTL3MBTL1CYP1A2 | |
| SCHEMBL4879063 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1MAPTL3MBTL1CYP1A2 | |
| SCHEMBL4985231 | 0.77 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPTL3MBTL1CYP1A2 | |
| SCHEMBL4367756 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1MAPTTDP1LMNA | |
| SCHEMBL15659545 | 0.77 | CYP2A6 (0.41) | KDM4EALDH1A1MAPTTDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106068-B2 | Compositions and methods for modulating c-kit and PDGFR receptors | IRM LLC (BM) | 2012-01-31 | — | — | US | disclosed |