SCHEMBL1002665

SCHEMBL1002665

C=CCc1cc(C=O)ccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.61
GABRB2 P47870 4/20 0.61
POLB P06746 2/20 0.57
KDM4E B2RXH2 3/20 0.53
PTGS2 P35354 2/20 0.53
RAB9A P51151 1/20 0.53
MEN1 O00255 2/20 0.49
GAA P10253 2/20 0.49
MAPT P10636 2/20 0.49
CNR1 P21554 2/20 0.49
CNR2 P34972 2/20 0.49
KMT2A Q03164 2/20 0.49
ALOX5 P09917 1/20 0.49
GABRB1 P18505 1/20 0.49
RXRA P19793 1/20 0.49
GABRA5 P31644 1/20 0.49
GABRA3 P34903 1/20 0.49
GABRA2 P47869 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
SIRT3 Q9NTG7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Magnaledehyde E SCHEMBL29732683 0.86 GABRA1 (0.67) GABRA1GABRB2POLBKDM4EPTGS2
SCHEMBL17694445 0.85 KDM4E (0.53) GABRA1GABRB2POLBKDM4EPTGS2
SCHEMBL4613626 0.85 GABRA1 (0.66) GABRA1GABRB2POLBKDM4EPTGS2
SCHEMBL7055923 0.82 KDM4E (0.45) GABRA1GABRB2POLBKDM4EPTGS2
SCHEMBL10071819 0.81 KDM4E (0.45) GABRA1GABRB2POLBKDM4EPTGS2
SCHEMBL8997040 0.81 GABRA1 (0.61) GABRA1GABRB2POLBKDM4EPTGS2
SCHEMBL7507833 0.80 KDM4E (0.61) KDM4EPTGS2RAB9AMEN1MAPT
SCHEMBL27948986 0.80 POLB (0.55) GABRA1GABRB2POLBKDM4EMEN1
SCHEMBL22296492 0.79 GABRA1 (0.58) GABRA1GABRB2POLBKDM4EPTGS2
SCHEMBL8159674 0.79 ALDH1A1 (0.45) GABRA1GABRB2POLBKDM4EPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 WO claimed
EP-1965753-B1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO KGAA (DE) 2013-09-04 EP claimed
US-7799096-B2 Agent for dyeing keratin-containing fibers HENKEL AG & CO. KGAA (DE) 2010-09-21 US claimed
US-20100064450-A1 AGENT FOR DYEING KERATIN-CONTAINING FIBERS HENKEL AG & CO. KGAA (DE) 2010-03-18 US claimed
EP-2069022-A2 AGENT FOR DYEING FIBERS COMPRISING KERATIN Henkel AG & Co. KGaA (DE) 2009-06-17 EP claimed
EP-2014275-A2 Kit for preparing storage-stable formulations Henkel AG & Co. KGaA (DE) 2009-01-14 EP claimed
US-20080301885-A1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO. KGAA (DE) 2008-12-11 US claimed
EP-1996145-A2 REDUCTIVE COLOUR REMOVAL Henkel AG & Co. KGaA (DE) 2008-12-03 EP claimed
EP-1888018-A1 AGENTS FOR DYEING KERATIN-BASED FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2008-02-20 EP claimed
EP-1879660-A1 AGENT FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-01-23 EP claimed
WO-2007107310-A2 REDUCTIVE COLOUR REMOVAL HENKEL AG & CO. KGAA (DE) 2007-09-27 WO claimed
WO-2007079802-A1 AGENT FOR DYEING KERATIN FIBERS HENKEL AG & CO. KGAA (DE) 2007-07-19 WO claimed
WO-2007073922-A1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO. KGAA (DE) 2007-07-05 WO claimed
WO-2006131163-A1 MULTICOMPONENT COMPOSITION FOR DYEING KERATIN FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-12-14 WO claimed
WO-2006119818-A1 AGENTS FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
WO-2006119819-A1 AGENT FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
WO-2006119820-A1 AGENTS FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed
US-4626584-A Crosslinkable thermotropic polyesters derived from allylically substituted hydroxybenzoic acid and a process for preparing a shaped article of the polyesters CELANESE CORPORATION (US) 1986-12-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100064450-A1 AGENT FOR DYEING KERATIN-CONTAINING FIBERS KRT18, CRYAA, CKAP4 GABRA1 4770/4885GABRB2 4789/4885POLB 1804/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO GABRA1 3586/4885GABRB2 3289/4885POLB 466/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO GABRA1 3586/4885GABRB2 3289/4885POLB 466/4885
US-20080301885-A1 REVERSIBLY CHANGEABLE HAIR COLOR TYR, CBR3, COXFA4L2 GABRA1 4587/4885GABRB2 4643/4885POLB 1507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.