Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | KDM5A | P29375 | 2/20 | 0.61 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.61 |
| ▸ | KDM4A | O75164 | 2/20 | 0.61 |
| ▸ | KDM5C | P41229 | 2/20 | 0.61 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.61 |
| ▸ | KDM6B | O15054 | 1/20 | 0.61 |
| ▸ | TET3 | O43151 | 1/20 | 0.61 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ASPH | Q12797 | 1/20 | 0.61 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.61 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.61 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.61 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.61 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.61 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.61 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11679600 | 0.98 | KDM4E (0.96) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A | |
| SCHEMBL5700497 | 0.81 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A | |
| SCHEMBL29478760 | 0.81 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A | |
| SCHEMBL7436876 | 0.81 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A | |
| SCHEMBL30141515 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A | |
| SCHEMBL31514843 | 0.81 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A | |
| SCHEMBL786245 | 0.81 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A | |
| SCHEMBL7513922 | 0.79 | KMO (0.71) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A | |
| SCHEMBL30800092 | 0.79 | KMO (0.71) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A | |
| SCHEMBL13188319 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2KDM5AKDM3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 752 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503553-B | Light affinity probe molecule based on VEGFR-2 inhibitor B14 and preparation method thereof | 西安交通大学 | 2020-08-28 | — | — | CN | claimed |
| CN-109503553-A | A kind of light Affinity Probes molecule and preparation method thereof based on VEGFR-2 inhibitor B14 | 西安交通大学 | 2019-03-22 | — | — | CN | claimed |
| CN-108752270-A | A kind of 4- bromo-2-pyridyl amides compounds of the ether structure containing hexichol | 湖南博隽生物医药有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-108516953-A | A kind of synthetic method of 2- pyridine carboxaldehydes derivative | 天津全和诚科技有限责任公司 | 2018-09-11 | — | — | CN | claimed |
| CN-104817493-A | Aromatic heterocyclic amide substituted diarylurea compound, preparation method and application thereof | UNIV XI AN JIAOTONG | 2015-08-05 | — | — | CN | claimed |
| CN-102977012-B | Synthesis method of methyl 4-bromopyridyl-2-formate | CHEMFUTURE PHARMATECH JIANGSU LTD | 2015-06-03 | — | — | CN | claimed |
| EP-2167077-A2 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-03-31 | — | — | EP | claimed |
| US-20090023741-A1 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AG (DE) | 2009-01-22 | — | — | US | claimed |
| WO-2008152099-A2 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| EP-3364967-B1 | FERROPORTIN INHIBITORS | VIFOR INT AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| US-20260078113-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORP (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4702025-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2026-03-04 | — | — | EP | disclosed |
| EP-4676926-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| US-12514858-B2 | CD38 inhibitors | Astellas Engineered Small Molecules US, Incorporated (US) | 2026-01-06 | — | — | US | disclosed |
| CN-1023479-C | Process for preparing monoamide derivatives of ethylenediamine | HOFFMANN LA ROCHE (CH) | 1994-01-12 | — | — | CN | disclosed |
| US-4764522-A | ANTIDEPRESSANT, ANTIPARKINSON DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1988-08-16 | — | — | US | disclosed |
| CN-85107182-A | Process for preparing monoamide derivatives of ethylenediamine | — | 1987-04-08 | — | — | CN | disclosed |
| EP-0053789-B1 | 2-PYRIDINECARBOXAMIDE DERIVATIVE, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITION, USEFUL AS AN ANTI-ALLERGIC AGENT | Tanabe Seiyaku Co., Ltd. (JP) | 1985-03-27 | — | — | EP | disclosed |
| US-4404214-A | 2-Pyridinecarboxamide derivatives compositions containing same and method of using same | TANABE SEIYAKU CO., LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0053789-A1 | 2-Pyridinecarboxamide derivative, process for preparing same and pharmaceutical composition, useful as an anti-allergic agent | Tanabe Seiyaku Co., Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023741-A1 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | PTGER2, PTGER1, PTGDR2 | KDM4E 3048/4885ALDH1A1 834/4885SMN1; SMN2 4144/4885 |
| US-20260078113-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | MSR1, NR3C1, CCR1 | KDM4E 4270/4885ALDH1A1 868/4885SMN1; SMN2 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.