Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | MC3R | P41968 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 3/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141515 | 1.00 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2DGAT1ADORA3 | |
| SCHEMBL31009108 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1SMN1; SMN2DGAT1ADORA3 | |
| SCHEMBL100727 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1SMN1; SMN2GRM5L3MBTL1 | |
| SCHEMBL29478760 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2TSHRGRM5 | |
| SCHEMBL7436876 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2PLGPLAU | |
| Hydrochloric Acid SCHEMBL11679600 | 0.79 | KDM4E (0.96) | KDM4EALDH1A1SMN1; SMN2GRM5L3MBTL1 | |
| SCHEMBL31514843 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2PLGPLAU | |
| Hydrochloric Acid SCHEMBL4524886 | 0.79 | SMN1; SMN2 (0.57) | KDM4EALDH1A1SMN1; SMN2DGAT1PARP1 | |
| SCHEMBL12851523 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2DGAT1PLG | |
| SCHEMBL5700497 | 0.79 | ALDH1A1 (0.68) | KDM4EALDH1A1SMN1; SMN2TSHRGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752270-A | A kind of 4- bromo-2-pyridyl amides compounds of the ether structure containing hexichol | 湖南博隽生物医药有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-105153023-B | The synthetic method of 2 amino, 4 bromopyridine | 成都同创源医药科技有限公司 | 2018-04-13 | — | — | CN | claimed |
| CN-105153023-A | Synthetic method of 2-amino-4-bromopyridine | CHENGDU TONGCHUANGYUAN PHARMACEUTICAL CO LTD | 2015-12-16 | — | — | CN | claimed |
| CN-101704781-B | Preparation method of amino pyridine bromide compound | UNIV JIANGSU POLYTECHNIC | 2012-05-30 | — | — | CN | claimed |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-22 | — | — | US | claimed |
| CN-101704781-A | Preparation method of amino pyridine bromide compound | UNIV JIANGSU POLYTECHNIC | 2010-05-12 | — | — | CN | claimed |
| US-20260034125-A1 | N-PHENYL-1-(PHENYLSULFONYL)PIPERIDIN-4-AMINE DERIVATIVES AS CCR6 INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2026-02-05 | — | — | US | disclosed |
| US-20250353859-A1 | COMPOUNDS AS CCR6 INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2025-11-20 | — | — | US | disclosed |
| US-20250339425-A1 | Alpha9 and Alpha7 Nicotinic Acetylcholine Receptor Ligands | UNIV NORTHEASTERN (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2025-09-25 | — | — | US | disclosed |
| US-20250276972-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) | 2025-09-04 | — | — | US | disclosed |
| EP-4551570-A1 | NOVEL COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Dong-A ST Co., Ltd. (KR) | 2025-05-14 | — | — | EP | disclosed |
| US-12240836-B2 | Compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | DONG-A ST CO., LTD. (KR) | 2025-03-04 | — | — | US | disclosed |
| WO-2008118455-A1 | δ3- SUBSTITUTED QUINOLINE OR QUINOXALINE DERIVATIVES AND THEIR USE AS PHOSPHATIDYLINOSITOL 3-KINASE ( PI3K) INHIBITORS | AMGEN INC. (US) | 2008-10-02 | — | — | WO | disclosed |
| EP-1289984-A4 | NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | DONG A PHARM CO LTD (KR) | 2004-11-24 | — | — | EP | disclosed |
| US-6689779-B2 | PYRIDINE OR PYRIMIDINE SUBSTITUTED; ANTIBACTERIAL ACTIVITY; LOW TOXICITY | DONG A PHARM. CO., LTD. (KR) | 2004-02-10 | — | — | US | disclosed |
| US-20030166620-A1 | Novel oxazolidinone derivatives and a process for the preparation thereof | DONG A PHARM. CO., LTD. (KR) | 2003-09-04 | — | — | US | disclosed |
| CN-1433413-A | Oxazolidinone derivatives and process for their preparation | DONG A PHARM CO LTD (KR) | 2003-07-30 | — | — | CN | disclosed |
| EP-1289984-A1 | NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | Dong A Pharmaceutical Co. Ltd. (KR) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001094342-A1 | NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | DONG A PHARM. CO., LTD. (KR) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250339425-A1 | Alpha9 and Alpha7 Nicotinic Acetylcholine Receptor Ligands | CHRNA9, CHRNA7, CHRNA1 | KDM4E 3415/4885ALDH1A1 1214/4885SMN1; SMN2 2910/4885 |
| US-20030166620-A1 | Novel oxazolidinone derivatives and a process for the preparation thereof | OXA1L, ODC1, PDCD4 | KDM4E 1158/4885ALDH1A1 939/4885SMN1; SMN2 3402/4885 |
| US-20250296915-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | KDM4E 4163/4885ALDH1A1 4626/4885SMN1; SMN2 3657/4885 |
| US-20110312935-A1 | 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents | MAPRE2, MAPRE1, H1-4 | KDM4E 140/4885ALDH1A1 1202/4885SMN1; SMN2 3446/4885 |
| US-12240836-B2 | Compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | EIF2AK4, GCN1, GCGR | KDM4E 4591/4885ALDH1A1 3927/4885SMN1; SMN2 3096/4885 |
| US-20260034125-A1 | N-PHENYL-1-(PHENYLSULFONYL)PIPERIDIN-4-AMINE DERIVATIVES AS CCR6 INHIBITORS | CCR6, CCR1, CCR4 | KDM4E 3365/4885ALDH1A1 1966/4885SMN1; SMN2 2462/4885 |
| US-20250353859-A1 | COMPOUNDS AS CCR6 INHIBITORS | CCR6, CCR4, CCR1 | KDM4E 1467/4885ALDH1A1 3366/4885SMN1; SMN2 2965/4885 |
| US-20250276972-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | PACSIN2, CSNK1A1, CSNK1G3 | KDM4E 1708/4885ALDH1A1 4340/4885SMN1; SMN2 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.