Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514843 | 1.00 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2GRM5MEN1 | |
| SCHEMBL100727 | 0.81 | KDM4E (1.00) | ALDH1A1KDM4ESMN1; SMN2GRM5MAPT | |
| SCHEMBL5700497 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2GRM5MEN1 | |
| SCHEMBL30141515 | 0.79 | KDM4E (0.68) | ALDH1A1KDM4ESMN1; SMN2GRM5MAPT | |
| Hydrochloric Acid SCHEMBL11679600 | 0.79 | KDM4E (0.96) | ALDH1A1KDM4ESMN1; SMN2GRM5MAPT | |
| SCHEMBL786245 | 0.79 | KDM4E (0.68) | ALDH1A1KDM4ESMN1; SMN2GRM5MAPT | |
| SCHEMBL29478760 | 0.79 | ALDH1A1 (0.68) | ALDH1A1KDM4ESMN1; SMN2GRM5MEN1 | |
| SCHEMBL11679598 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2GRM5MEN1 | |
| SCHEMBL9772775 | 0.78 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2GRM5MEN1 | |
| Lithium Ion SCHEMBL31704468 | 0.78 | KDM4E (0.66) | ALDH1A1KDM4ESMN1; SMN2GRM5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024158698-A1 | NOVEL F-ATPASE HYDROLASE INHIBITORS | LUCY THERAPEUTICS, INC. (US) | 2024-08-02 | — | — | WO | disclosed |
| CN-115433203-A | Amine fluorinated curcumenol derivative compound and application and preparation method thereof | 华东理工大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-108191761-B | Heterocyclic compound and organic light-emitting device using the same | LT素材株式会社 | 2021-12-21 | — | — | CN | disclosed |
| CN-111712490-A | Amino-substituted pyridone derivatives, preparation method and medical application thereof | 上海海雁医药科技有限公司 | 2020-09-25 | — | — | CN | disclosed |
| WO-2020182018-A1 | NITROGEN HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2020-09-17 | — | — | WO | disclosed |
| EP-3088392-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | HEESUNG MAT LTD (KR) | 2020-03-11 | — | — | EP | disclosed |
| US-9728731-B2 | Heterocyclic compound and organic light emitting device using same | HEESUNG MATERIAL LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-9728731-B2 | Heterocyclic compound and organic light emitting device using same | HEESUNG MATERIAL LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-9728731-B2 | Heterocyclic compound and organic light emitting device using same | HEESUNG MATERIAL LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-20160380208-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | HEESUNG MATERIAL LTD. (KR) | 2016-12-29 | — | — | US | disclosed |
| EP-3088392-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | Heesung Material Ltd. (KR) | 2016-11-02 | — | — | EP | disclosed |
| EP-2755973-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINES, THEIR USE AS MEDICAMENT, AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | SANOFI SA (FR) | 2015-11-04 | — | — | EP | disclosed |
| CN-104817493-A | Aromatic heterocyclic amide substituted diarylurea compound, preparation method and application thereof | UNIV XI AN JIAOTONG | 2015-08-05 | — | — | CN | disclosed |
| EP-2808324-A1 | PYRROLE COMPOUND | Kabushiki Kaisha Yakult Honsha (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-20140343017-A1 | PYRROLE COMPOUND | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2014-11-20 | — | — | US | disclosed |
| CN-104080783-A | Pyrrole compounds | YAKULT HONSHA KK | 2014-10-01 | — | — | CN | disclosed |
| US-4405628-A | 4-Pyridylimidazolones and method of use | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-09-20 | — | — | US | disclosed |
| EP-0059948-A1 | Novel aroylimidazolones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4046768-A | 1-Thiazolyl-5-pyridylcarbonyloxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |
| US-4033753-A | HERICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343017-A1 | PYRROLE COMPOUND | TUBB3, TUBB1, TUBB | ALDH1A1 2354/4885KDM4E 2403/4885SMN1; SMN2 1580/4885 |
| US-20160380208-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | NOTUM, DDT, CRY1 | ALDH1A1 85/4885KDM4E 1977/4885SMN1; SMN2 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.