SCHEMBL10073146

SCHEMBL10073146

NCCC(O)(O[PH](=O)O)O[PH](=O)O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
ADRB3 P13945 1/20 0.34
FDPS P14324 1/20 0.34
PDE4D Q08499 1/20 0.34
PDE3A Q14432 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1668785 0.86 FDPS (0.39) FDPSPDE3A
SCHEMBL14217571 0.84
SCHEMBL10073144 0.83 FDPS (0.42) LMNAFDPSPDE3A
SCHEMBL12848975 0.80
SCHEMBL15492658 0.76
SCHEMBL13334580 0.74
SCHEMBL8259996 0.73 FDPS (0.32) FDPSPDE3A
SCHEMBL14942976 0.73 ADH1B (0.32)
SCHEMBL16327574 0.73
SCHEMBL15492659 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170164642-A1 Preservative System For Acidic Beverages Based On Sequestrants PEPSICO, INC. 2017-06-15 US disclosed
US-9560871-B2 Preservative system for acidic beverages based on sequestrants PEPSICO, INC. (US) 2017-02-07 US disclosed
WO-2012054807-A2 VACCINES COMPRISING BISPHOSPHONATE AND METHODS OF USE THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2012-04-26 WO disclosed
US-7902310-B2 Use as additives for inorganic binding agent suspensions based on cement, lime, gypsum and anhydrite; improve processing and setting processes of building materials produced with these additives by making possible earlier and higher resistances to pressure CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2011-03-08 US disclosed
US-20100166917-A1 Preservative System For Acidic Beverages Based On Sequestrants PEPSICO, INC. (US) 2010-07-01 US disclosed
US-20080317834-A1 Compounds and methods for modulating cerebral amyloid angiopathy NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2008-12-25 US disclosed
US-20080220037-A1 Biphosphonic Compounds For Preventing Or Limiting Fixing Of Macromolecules, Microorganisms And Biofilm On Solid, In Particular Metal Or Mineral Surfaces SURFACTIS TECHNOLOGIES (FR) 2008-09-11 US disclosed
US-20080125520-A1 Copolymers Base on Phosphorous-Containing Monomers, Methods for the Production Thereof and Their Use CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2008-05-29 US disclosed
US-20070078082-A1 Methods and compositions to treat glycosaminoglycan-associated molecular interactions NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2007-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080220037-A1 Biphosphonic Compounds For Preventing Or Limiting Fixing Of Macromolecules, Microorganisms And Biofilm On Solid, In Particular Metal Or Mineral Surfaces BPGM, FIBP, SOST LMNA 4002/4885ADRB3 4883/4885FDPS 65/4885
US-20080317834-A1 Compounds and methods for modulating cerebral amyloid angiopathy APP, PYGB, MAPT LMNA 1103/4885ADRB3 576/4885FDPS 1920/4885
US-20070078082-A1 Methods and compositions to treat glycosaminoglycan-associated molecular interactions HPSE, CD44, CSGALNACT1 LMNA 2106/4885ADRB3 4557/4885FDPS 4229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.