Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074479 | 0.88 | KLK7 (0.44) | FKBP1AMMP2ANPEPPSEN1PSEN2 | |
| SCHEMBL1006401 | 0.77 | MMP2 (0.36) | MMP2ANPEPKMT2ATSHRALDH1A1 | |
| SCHEMBL1004592 | 0.70 | MMP2 (0.37) | MMP2ANPEPKMT2AMAPT | |
| SCHEMBL1003699 | 0.70 | SIGMAR1 (0.36) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL14893328 | 0.69 | ALDH1A1 (0.46) | FKBP1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2579480 | 0.69 | P2RX7 (0.55) | FKBP1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2579481 | 0.69 | P2RX7 (0.55) | FKBP1APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL17442799 | 0.67 | DRD2 (0.55) | DRD2DRD4 | |
| SCHEMBL9753059 | 0.67 | ALDH1A1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9753061 | 0.67 | ALDH1A1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011330-A2 | INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2011-01-27 | — | — | WO | disclosed |