Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438877 | 0.93 | HSD17B10 (0.56) | HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15120766 | 0.84 | HSD17B10 (0.68) | HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10084268 | 0.81 | HSD17B10 (0.64) | HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15119804 | 0.78 | CETP (0.56) | HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL17896349 | 0.77 | HPGD (0.60) | HSD17B10SMN1; SMN2ALDH1A1HPGDPOLB | |
| SCHEMBL4603679 | 0.76 | SMN1; SMN2 (0.74) | HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31058408 | 0.74 | MAPK1 (0.63) | HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15587329 | 0.72 | HPGD (0.64) | HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL2678590 | 0.72 | HSD17B10 (0.56) | HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31195837 | 0.72 | HSD17B10 (0.56) | HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130184456-A1 | HETEROCYCLIC MACROCYCLE TEMPLATED METAL-ORGANIC MATERIALS | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130023403-A1 | METAL ORGANIC MATERIALS AS BIOMIMETIC ENZYMES | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-01-24 | — | — | US | disclosed |
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | NATIONAL SCIENCE FOUNDATION | 2012-02-23 | — | — | US | disclosed |
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | NATIONAL SCIENCE FOUNDATION | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046455-A1 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates | PPOX, POR, PCCA | HSD17B10 669/4885KDM4E 3545/4885SMN1; SMN2 3724/4885 |
| US-20110207956-A1 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES | CYCS, CCNH, CBR3 | HSD17B10 3091/4885KDM4E 3248/4885SMN1; SMN2 3875/4885 |
| US-20130184456-A1 | HETEROCYCLIC MACROCYCLE TEMPLATED METAL-ORGANIC MATERIALS | ORC3, MCM4, MCM7 | HSD17B10 3912/4885KDM4E 3100/4885SMN1; SMN2 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.