Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073854 | 0.93 | HSD17B10 (0.64) | HSD17B10SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL15120766 | 0.78 | HSD17B10 (0.68) | HSD17B10SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL10084268 | 0.75 | HSD17B10 (0.64) | HSD17B10SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL15119804 | 0.72 | CETP (0.56) | HSD17B10SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL17896349 | 0.72 | HPGD (0.60) | HSD17B10SMN1; SMN2HPGDALDH1A1POLB | |
| SCHEMBL4603679 | 0.70 | SMN1; SMN2 (0.74) | HSD17B10SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL3438874 | 0.70 | GAA (0.41) | SMN1; SMN2KDM4EHPGDHTTLMNA | |
| SCHEMBL31058408 | 0.68 | MAPK1 (0.63) | HSD17B10SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL15587329 | 0.67 | HPGD (0.64) | HSD17B10SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL22332735 | 0.67 | TDP1 (0.49) | HSD17B10SMN1; SMN2KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101271-A1 | DIAMINE SYNTHESIS VIA CATALYTIC C-H AMINATION OF AZIDES | NATIONAL SCIENCE FOUNDATION | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101271-A1 | DIAMINE SYNTHESIS VIA CATALYTIC C-H AMINATION OF AZIDES | DOHH, AOC1, ESD | HSD17B10 4123/4885SMN1; SMN2 1784/4885KDM4E 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.