SCHEMBL10075733

SCHEMBL10075733

CC(=O)O/N=C(\C)C(=O)c1ccc(Sc2ccc(OCO)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.39
KMT2A Q03164 2/20 0.39
PKM P14618 2/20 0.39
LMNA P02545 4/20 0.39
HPGD P15428 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.37
GAA P10253 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
ALDH1A1 P00352 2/20 0.36
PTGIR P43119 1/20 0.35
PARP10 Q53GL7 1/20 0.35
THRB P10828 1/20 0.34
MAPT P10636 2/20 0.34
PTPRC P08575 2/20 0.33
PTPN1 P18031 2/20 0.33
POLB P06746 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPRF P10586 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20783443 0.90 GAA (0.43) L3MBTL1KMT2APKMLMNAHPGD
SCHEMBL10075727 0.90 GAA (0.43) L3MBTL1KMT2APKMLMNAHPGD
SCHEMBL22639048 0.90 GAA (0.43) L3MBTL1KMT2APKMLMNAHPGD
SCHEMBL23550803 0.90 PARP10 (0.48) L3MBTL1KMT2APKMLMNAHPGD
SCHEMBL10075730 0.89 L3MBTL1 (0.42) L3MBTL1KMT2APKMLMNAHPGD
SCHEMBL20935148 0.87 L3MBTL1 (0.50) L3MBTL1KMT2APKMLMNAHPGD
SCHEMBL14900204 0.87 PKM (0.40) L3MBTL1KMT2APKMLMNAHPGD
SCHEMBL10075750 0.87 SMN1; SMN2 (0.41) L3MBTL1KMT2APKMLMNAHPGD
SCHEMBL21870374 0.86 L3MBTL1 (0.39) L3MBTL1KMT2APKMLMNAHPGD
SCHEMBL10075826 0.86 L3MBTL1 (0.39) L3MBTL1KMT2APKMLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2586827-B1 CURABLE RESIN COMPOSITION ADEKA CORP (JP) 2017-12-27 EP disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
EP-2327689-A1 Oxime ester compound and photopolymerization initiator containing the same Adeka Corporation (JP) 2011-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME OXER1, OR10J3, CDK11B L3MBTL1 1628/4885KMT2A 3531/4885PKM 2560/4885
US-20120115972-A1 CURING RESIN COMPOSITION LTA, LOXL1, PLOD2 L3MBTL1 228/4885KMT2A 247/4885PKM 3591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.