SCHEMBL10075752

SCHEMBL10075752

CC(=O)O/N=C(\C)C(=O)c1ccc(Sc2ccc(O)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
HPGD P15428 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KMT2A Q03164 3/20 0.43
NR1H2 P55055 1/20 0.42
ALDH1A1 P00352 2/20 0.40
CPT1B Q92523 1/20 0.38
CES2 O00748 1/20 0.37
MAPT P10636 5/20 0.37
MEN1 O00255 2/20 0.37
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA14 Q9ULX7 2/20 0.36
HSD17B1 P14061 1/20 0.36
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PKM P14618 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20935148 0.94 L3MBTL1 (0.50) LMNAHPGDL3MBTL1KMT2AALDH1A1
SCHEMBL19795439 0.88 L3MBTL1 (0.57) LMNAHPGDL3MBTL1KMT2AALDH1A1
SCHEMBL19795435 0.88 HPGD (0.56) LMNAHPGDL3MBTL1KMT2AALDH1A1
SCHEMBL10075708 0.88 HPGD (0.44) LMNAHPGDL3MBTL1KMT2AALDH1A1
SCHEMBL16019156 0.88 HPGD (0.56) LMNAHPGDL3MBTL1KMT2AALDH1A1
SCHEMBL24489413 0.88 L3MBTL1 (0.44) LMNAHPGDL3MBTL1KMT2AALDH1A1
SCHEMBL19751020 0.84 L3MBTL1 (0.41) LMNAHPGDL3MBTL1KMT2AALDH1A1
SCHEMBL10075710 0.82 L3MBTL1 (0.45) LMNAHPGDL3MBTL1KMT2AALDH1A1
SCHEMBL23550803 0.82 PARP10 (0.48) LMNAHPGDL3MBTL1KMT2AALDH1A1
SCHEMBL10075733 0.82 L3MBTL1 (0.39) LMNAHPGDL3MBTL1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438134-A1 POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL FILM FOR DISPLAY, AND PROCESS FOR PRODUCING CURED OBJECT Adeka Corporation (JP) 2019-02-06 EP disclosed
EP-2586827-B1 CURABLE RESIN COMPOSITION ADEKA CORP (JP) 2017-12-27 EP disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
EP-2327689-B1 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORP (JP) 2012-02-29 EP disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
EP-2327689-A1 Oxime ester compound and photopolymerization initiator containing the same Adeka Corporation (JP) 2011-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME OXER1, OR10J3, CDK11B LMNA 3014/4885HPGD 1805/4885L3MBTL1 1628/4885
US-20120115972-A1 CURING RESIN COMPOSITION LTA, LOXL1, PLOD2 LMNA 997/4885HPGD 654/4885L3MBTL1 228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.