SCHEMBL10075755

SCHEMBL10075755

CCCCC(=O)OCCOc1ccc(Sc2ccc(C(=O)/C(C)=N/OC(C)=O)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 1/20 0.40
MMP1 P03956 1/20 0.40
FAAH O00519 3/20 0.38
GAA P10253 1/20 0.38
RAB9A P51151 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
PLA2G4B P0C869 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
RARB P10826 1/20 0.37
PRSS1 P07477 1/20 0.37
ACR P10323 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075826 0.88 L3MBTL1 (0.39) L3MBTL1MAPTGAARAB9ATSHR
SCHEMBL10075801 0.85 L3MBTL1 (0.35) L3MBTL1MAPTGAATSHR
SCHEMBL20709713 0.84 L3MBTL1 (0.38) L3MBTL1MAPTRAB9ASMN1; SMN2
SCHEMBL10075730 0.83 L3MBTL1 (0.42) L3MBTL1MAPTFAAHGAARAB9A
SCHEMBL31098997 0.83 POLB (0.48) L3MBTL1MAPTGAARAB9ASMN1; SMN2
SCHEMBL10075831 0.83 THRA (0.44) L3MBTL1MAPTGAASMN1; SMN2RARB
SCHEMBL10075727 0.82 GAA (0.43) L3MBTL1MAPTGAATSHRSMN1; SMN2
SCHEMBL20783443 0.82 GAA (0.43) L3MBTL1MAPTGAATSHRSMN1; SMN2
SCHEMBL22639048 0.82 GAA (0.43) L3MBTL1MAPTGAATSHRSMN1; SMN2
SCHEMBL21870374 0.81 L3MBTL1 (0.39) L3MBTL1MAPTGAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2586827-B1 CURABLE RESIN COMPOSITION ADEKA CORP (JP) 2017-12-27 EP disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
EP-2586827-A1 CURABLE RESIN COMPOSITION Adeka Corporation (JP) 2013-05-01 EP disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
EP-2327689-B1 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORP (JP) 2012-02-29 EP disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
EP-2327689-A1 Oxime ester compound and photopolymerization initiator containing the same Adeka Corporation (JP) 2011-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME OXER1, OR10J3, CDK11B L3MBTL1 1628/4885MAPT 3494/4885MMP1 4291/4885
US-20120115972-A1 CURING RESIN COMPOSITION LTA, LOXL1, PLOD2 L3MBTL1 228/4885MAPT 154/4885MMP1 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.