SCHEMBL10075799

SCHEMBL10075799

CC(=O)O/N=C(\C)C(=O)c1ccc(Sc2ccc(OCCC(=O)SCCO)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.36
GAA P10253 3/20 0.36
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.33
MMP1 P03956 1/20 0.33
PKM P14618 1/20 0.33
FURIN P09958 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC10 Q969S8 1/20 0.32
HDAC11 Q96DB2 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
ESRRB O95718 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075730 0.88 L3MBTL1 (0.42) L3MBTL1GAAMAPTKMT2APKM
SCHEMBL20783443 0.87 GAA (0.43) L3MBTL1GAAMAPTKMT2APKM
SCHEMBL22639048 0.87 GAA (0.43) L3MBTL1GAAMAPTKMT2APKM
SCHEMBL10075727 0.87 GAA (0.43) L3MBTL1GAAMAPTKMT2APKM
SCHEMBL10075801 0.85 L3MBTL1 (0.35) L3MBTL1GAAMAPTKMT2APKM
SCHEMBL10075824 0.82 L3MBTL1 (0.38) L3MBTL1GAAMAPTKMT2APKM
SCHEMBL10075733 0.82 L3MBTL1 (0.39) L3MBTL1GAAMAPTKMT2APKM
SCHEMBL21870374 0.81 L3MBTL1 (0.39) L3MBTL1GAAMAPTKMT2APKM
SCHEMBL10075826 0.81 L3MBTL1 (0.39) L3MBTL1GAAMAPTKMT2APKM
SCHEMBL10075820 0.80 L3MBTL1 (0.39) L3MBTL1GAAMAPTKMT2AMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2586827-B1 CURABLE RESIN COMPOSITION ADEKA CORP (JP) 2017-12-27 EP disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
EP-2586827-A1 CURABLE RESIN COMPOSITION Adeka Corporation (JP) 2013-05-01 EP disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
EP-2327689-A1 Oxime ester compound and photopolymerization initiator containing the same Adeka Corporation (JP) 2011-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME OXER1, OR10J3, CDK11B L3MBTL1 1628/4885GAA 4794/4885MAPT 3494/4885
US-20120115972-A1 CURING RESIN COMPOSITION LTA, LOXL1, PLOD2 L3MBTL1 228/4885GAA 3567/4885MAPT 154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.