SCHEMBL10075827

SCHEMBL10075827

CC(=O)O/N=C(\C)C(=O)c1ccc(Sc2ccc(C(=O)OCCOc3ccccc3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.45
RAB9A P51151 5/20 0.45
PARP10 Q53GL7 1/20 0.41
ALDH1A1 P00352 5/20 0.41
MMP1 P03956 1/20 0.40
MMP12 P39900 1/20 0.40
NPC1 O15118 4/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 2/20 0.40
PKM P14618 2/20 0.40
MEN1 O00255 2/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
HSD17B10 Q99714 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10075826 0.88 L3MBTL1 (0.39) MAPTRAB9APARP10ALDH1A1KMT2A
SCHEMBL10075825 0.85 KMT2A (0.51) MAPTALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL10075760 0.84 L3MBTL1 (0.44) MAPTRAB9AALDH1A1NPC1KMT2A
SCHEMBL10075808 0.84 L3MBTL1 (0.41) ALDH1A1KMT2AKDM4ESMN1; SMN2HPGD
SCHEMBL10075709 0.84 L3MBTL1 (0.43) MAPTRAB9AALDH1A1NPC1KMT2A
SCHEMBL31098997 0.83 POLB (0.48) MAPTRAB9APARP10ALDH1A1KMT2A
SCHEMBL10075753 0.82 L3MBTL1 (0.43) MAPTRAB9AALDH1A1NPC1KMT2A
SCHEMBL10075804 0.82 L3MBTL1 (0.43) MAPTRAB9AALDH1A1NPC1KMT2A
SCHEMBL19795435 0.82 HPGD (0.56) MAPTRAB9AALDH1A1NPC1KMT2A
SCHEMBL16019156 0.82 HPGD (0.56) MAPTRAB9AALDH1A1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2586827-B1 CURABLE RESIN COMPOSITION ADEKA CORP (JP) 2017-12-27 EP disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
US-8735511-B2 Curing resin composition ADEKA CORPORATION (JP) 2014-05-27 US disclosed
EP-2586827-A1 CURABLE RESIN COMPOSITION Adeka Corporation (JP) 2013-05-01 EP disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-20120115972-A1 CURING RESIN COMPOSITION ADEKA CORPORATION (JP) 2012-05-10 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
US-8148045-B2 Oxime ester compound and photopolymerization initiator containing the same ADEKA CORPORATION (JP) 2012-04-03 US disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME ADEKA CORPORATION (JP) 2011-06-02 US disclosed
EP-2327689-A1 Oxime ester compound and photopolymerization initiator containing the same Adeka Corporation (JP) 2011-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110129778-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING THE SAME OXER1, OR10J3, CDK11B MAPT 3494/4885RAB9A 3932/4885PARP10 495/4885
US-20120115972-A1 CURING RESIN COMPOSITION LTA, LOXL1, PLOD2 MAPT 154/4885RAB9A 3603/4885PARP10 3515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.