SCHEMBL10075825

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10075827	0.85	MAPT (0.45)	KMT2AMEN1MAPTLMNAPOLB
	SCHEMBL10075780	0.85	ALDH1A1 (0.39)	KMT2AMEN1MAPTADRB2ADRB1
	SCHEMBL10075768	0.83	L3MBTL1 (0.41)	KMT2AMAPTADRB2ADRB1ADRB3
	SCHEMBL10075792	0.82	ABCB1 (0.39)	KMT2AMEN1MAPTLMNAPOLB
	SCHEMBL16019156	0.79	HPGD (0.56)	KMT2AMAPTLMNAPOLBALDH1A1
	SCHEMBL19795435	0.79	HPGD (0.56)	KMT2AMAPTLMNAPOLBALDH1A1
	SCHEMBL10075710	0.78	L3MBTL1 (0.45)	KMT2AMEN1MAPTLMNAPOLB
	SCHEMBL10075797	0.78	KMT2A (0.36)	KMT2AMEN1MAPTADRB2ADRB1
	SCHEMBL12865769	0.78	MEN1 (0.77)	KMT2AMEN1MAPTADRB2ADRB1
	SCHEMBL10075808	0.76	L3MBTL1 (0.41)	KMT2ALMNAALDH1A1CYP2D6L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.