Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11850339 | 1.00 | CA4 (0.47) | — | |
| Lithium Ion SCHEMBL6352034 | 0.92 | — | — | |
| SCHEMBL10490552 | 0.92 | ALDH1A1 (0.47) | — | |
| SCHEMBL7045610 | 0.92 | — | — | |
| SCHEMBL7042120 | 0.92 | — | — | |
| SCHEMBL4754719 | 0.92 | — | — | |
| SCHEMBL1681011 | 0.92 | ALDH1A1 (0.47) | — | |
| SCHEMBL18154635 | 0.92 | ALDH1A1 (0.47) | — | |
| SCHEMBL7627644 | 0.92 | ALDH1A1 (0.47) | — | |
| SCHEMBL27575014 | 0.92 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720436-A | Organic crystal with thermal phase transition induced mechanical behavior and fluorescence enhancement and preparation method and application thereof | 广西民族大学 | 2024-03-19 | — | — | CN | claimed |
| CN-111440220-B | Method for preparing high-purity stevioside RC from mother liquor sugar | 浙江天草生物科技股份有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-115490679-A | D-pi-A structure tri-substituted olefin with high affinity with alpha-synuclein, and preparation method and application thereof | 北京核素医药科技有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-113698286-A | Preparation method of p-hydroxybenzoic acid | 宿迁思睿屹新材料有限公司 | 2021-11-26 | — | — | CN | claimed |
| CN-107466289-B | Process for producing ethylenically unsaturated carboxylic acids or esters | 三菱化学英国有限公司 | 2021-09-17 | — | — | CN | claimed |
| EP-3283456-B1 | A PROCESS FOR THE PRODUCTION OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS OR ESTERS | MITSUBISHI CHEMICAL UK LTD (GB) | 2021-06-23 | — | — | EP | claimed |
| CN-110804175-B | Antibacterial polyamino acid derivative or copolymer with alternating structure and preparation method thereof | 中国科学院理化技术研究所 | 2021-05-14 | — | — | CN | claimed |
| CN-111253457-B | Method for preparing 16alpha-hydroxy prednisolone | 浙江神洲药业有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-111440220-A | Method for preparing high-purity stevioside RC from mother liquor sugar | 浙江天草生物科技股份有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-111269102-A | Method for extracting phorbol from croton oil by using Giralde reagent | 南昌大学 | 2020-06-12 | — | — | CN | claimed |
| US-10464875-B2 | Process for the production of ethylenically unsaturated carboxylic acids or esters | LUCITE INTERNATIONAL UK LIMITED (GB) | 2019-11-05 | — | — | US | claimed |
| US-20180093937-A1 | PROCESS FOR THE PRODUCTION OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS OR ESTERS | Mitsubishi Chemical UK Limited (GB) | 2018-04-05 | — | — | US | claimed |
| EP-3283456-A1 | A PROCESS FOR THE PRODUCTION OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS OR ESTERS | Lucite International UK Limited (GB) | 2018-02-21 | — | — | EP | claimed |
| CN-107325809-A | A kind of and A β plaque block has fluorescent chemicals and the preparation and application of affinity | 华南理工大学 | 2017-11-07 | — | — | CN | claimed |
| WO-2016166525-A1 | A PROCESS FOR THE PRODUCTION OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS OR ESTERS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2016-10-20 | — | — | WO | claimed |
| US-7208613-B2 | Synthesis of s-fluoromethyl 6α,9α-difluoro-11β-hydroxy-16α-methyl-17α-propionyloxy-3-oxoandrosta-1,4-diene-17β-carbothioate | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2007-04-24 | — | — | US | claimed |
| US-20050256325-A1 | Convenient synthesis of s-fluoromethyl 6alpha, 9alpha-difluoro-11beta-hydroxy-16alpha-methyl-17alpha-propionyloxy-3-oxoandrosta-1,4-diene-17beta-carbothioate | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2005-11-17 | — | — | US | claimed |
| EP-1534733-A2 | CONVENIENT SYNTHESIS OF S-FLUOROMETHYL 6ALPHA, 9ALPHA-DIFLUORO-11BETA-HYDROXY-16ALPHA- METHYL-17ALPHA-PROPIONYLOXY-3-OXOANDROSTA-1, 4-DIENE-17BETA-CARBOTHIOATE | Sun Pharmaceuticals Industries Ltd. (IN) | 2005-06-01 | — | — | EP | claimed |
| WO-2004001369-A2 | CONVENIENT SYNTHESIS OF S-FLUOROMETHYL 6ALPHA, 9ALPHA-DIFLUORO-11BETA-HYDROXY-16ALPHA- METHYL-17ALPHA-PROPIONYLOXY-3-OXOANDROSTA-1, 4-DIENE-17BETA-CARBOTHIOATE | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2003-12-31 | — | — | WO | claimed |
| US-4950750-A | Glycolipid containing N-glycolylneuraminic acid and method of producing the same | MECT CORPORATION (JP) | 1990-08-21 | — | — | US | claimed |