Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10076958 | 0.89 | TDP1 (0.36) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL526306 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL10077797 | 0.74 | HIF1A (0.35) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL526307 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL22117258 | 0.66 | RAB9A (0.44) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL968214 | 0.66 | VCAM1 (0.54) | ALDH1A1KMT2AMAPK1MAPTMEN1 | |
| SCHEMBL2337212 | 0.66 | CA1 (0.51) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL4381121 | 0.65 | KMT2A (0.50) | KMT2ATDP1MEN1PKMCA12 | |
| SCHEMBL20564486 | 0.65 | KMT2A (0.58) | ALDH1A1KMT2ATDP1MAPK1MAPT | |
| SCHEMBL31039461 | 0.65 | KMT2A (0.58) | ALDH1A1KMT2ATDP1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014147-A1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-02 | — | — | WO | disclosed |