Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526531 | 0.77 | NR1D1 (0.38) | HIF1ANR1D1KMT2AALDH1A1MAPK1 | |
| SCHEMBL10077084 | 0.74 | ALDH1A1 (0.39) | KMT2AALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL530068 | 0.73 | NR1D1 (0.43) | NR1D1KMT2ATDP1MEN1MET | |
| SCHEMBL18900250 | 0.73 | NR1D1 (0.35) | HIF1ANR1D1KMT2AALDH1A1MAPK1 | |
| SCHEMBL530360 | 0.73 | NR1D1 (0.46) | NR1D1KMT2AALDH1A1TDP1MEN1 | |
| SCHEMBL10076735 | 0.73 | NR1D1 (0.42) | NR1D1KMT2ATDP1MEN1MET | |
| SCHEMBL10076958 | 0.71 | TDP1 (0.36) | KMT2AALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL530308 | 0.71 | NR1D1 (0.40) | NR1D1KMT2AALDH1A1MEN1MET | |
| SCHEMBL530309 | 0.69 | NR1D1 (0.37) | NR1D1KMT2AALDH1A1TDP1MEN1 | |
| SCHEMBL17089907 | 0.69 | NR1D1 (0.42) | NR1D1KMT2AALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014147-A1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-02 | — | — | WO | disclosed |