Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077084 | 0.89 | ALDH1A1 (0.39) | TDP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL526222 | 0.76 | MAPT (0.41) | TDP1MAPTSLC10A6MEN1KMT2A | |
| SCHEMBL526223 | 0.72 | TDP1 (0.40) | TDP1MAPTSLC10A6MEN1KMT2A | |
| SCHEMBL10077797 | 0.71 | HIF1A (0.35) | TDP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL20089218 | 0.70 | NR1D1 (0.51) | TDP1MAPTSLC10A6MEN1KMT2A | |
| SCHEMBL5640330 | 0.70 | KMT2A (0.45) | TDP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13242356 | 0.69 | TDP1 (0.55) | TDP1MAPTSLC10A6MEN1KMT2A | |
| SCHEMBL17089907 | 0.69 | NR1D1 (0.42) | TDP1MAPTSLC10A6MEN1KMT2A | |
| SCHEMBL29238398 | 0.68 | MEN1 (0.51) | MAPTSLC10A6MEN1KMT2AALDH1A1 | |
| SCHEMBL25228512 | 0.68 | SLC10A6 (0.43) | TDP1MAPTSLC10A6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014147-A1 | ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-02 | — | — | WO | disclosed |