SCHEMBL10077574

SCHEMBL10077574

NC(CCN1C(=O)C=CC1=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM5 P41594 2/20 0.46
▸ GRM2 Q14416 2/20 0.46
▸ PTGS1 P23219 5/20 0.46
▸ PTGS2 P35354 4/20 0.46
▸ MGLL Q99685 4/20 0.45
▸ FAAH O00519 2/20 0.45
▸ HSP90AA1 P07900 1/20 0.43
▸ TLR9 Q9NR96 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ PKM P14618 1/20 0.43
▸ HPGD P15428 1/20 0.43
▸ XBP1 P17861 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14679245 0.87 MGLL (0.55) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL22687997 0.87 MGLL (0.55) PTGS1PTGS2MGLLFAAHHSP90AA1
Hydrochloric Acid SCHEMBL28705925 0.86 MGLL (0.53) PTGS1PTGS2MGLLFAAHHSP90AA1
Hydrochloric Acid SCHEMBL22657875 0.86 MGLL (0.53) PTGS1PTGS2MGLLFAAHHSP90AA1
Hydrochloric Acid SCHEMBL22657871 0.86 MGLL (0.53) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL547101 0.82 GRM2 (0.39) GRM5GRM2ALDH1A1GSRGRM8
SCHEMBL31133605 0.81 PTGS1 (0.51) PTGS1PTGS2MGLLFAAHHSP90AA1
SCHEMBL27562071 0.80 KDM4E (0.45) GRM5PTGS1PTGS2ALDH1A1PKM
SCHEMBL22069851 0.80 LTA4H (0.43) GRM5GRM2PTGS1PTGS2GSR
SCHEMBL22069850 0.80 LTA4H (0.43) GRM5GRM2PTGS1PTGS2GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9340567-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2016-05-17 — — US disclosed
US-9340567-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2016-05-17 — — US disclosed
US-20150198552-A9 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2015-07-16 — — US disclosed
US-20150198552-A9 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2015-07-16 — — US disclosed
US-8951400-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2015-02-10 — — US disclosed
US-8951400-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2015-02-10 — — US disclosed
US-20140311922-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2014-10-23 — — US disclosed
US-20140311922-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2014-10-23 — — US disclosed
US-8734631-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2014-05-27 — — US disclosed
US-8734631-B2 Chemistry used in biosensors OHMX CORPORATION (US) 2014-05-27 — — US disclosed
WO-2013067349-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2013-05-10 — — WO disclosed
US-20130112572-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2013-05-09 — — US disclosed
US-20130112572-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2013-05-09 — — US disclosed
WO-2012012537-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2012-01-26 — — WO disclosed
US-20120012472-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2012-01-19 — — US disclosed
US-20120012472-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2012-01-19 — — US disclosed
US-20090253149-A1 Novel Chemistry Used in Biosensors OHMX CORPORATION (US) 2009-10-08 — — US disclosed
US-20090253149-A1 Novel Chemistry Used in Biosensors OHMX CORPORATION (US) 2009-10-08 — — US disclosed
WO-2009052436-A1 NOVEL CHEMISTRY USED IN BIOSENSORS OHMX CORPORATION (US) 2009-04-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120012472-A1 NOVEL CHEMISTRY USED IN BIOSENSORS SSBP1, OSGEP, OCIAD2 GRM5 3341/4885GRM2 3602/4885PTGS1 4497/4885
US-20130112572-A1 NOVEL CHEMISTRY USED IN BIOSENSORS GPX1, GPX4, FECH GRM5 1846/4885GRM2 1205/4885PTGS1 2901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback