Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13103343 | 1.00 | KMT2A (0.56) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL100984 | 0.91 | KMT2A (0.50) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL27647042 | 0.91 | KMT2A (0.50) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL20613616 | 0.88 | KMT2A (0.46) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL25486009 | 0.77 | MAOB (0.58) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL22808244 | 0.76 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL20881023 | 0.76 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL998879 | 0.76 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL16167075 | 0.76 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ANFKB1 | |
| SCHEMBL19530361 | 0.76 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957392-B2 | Fluorescent probe for imaging lymph nodes | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2018-05-01 | — | — | US | disclosed |
| US-9872833-B2 | Liposome composite body | NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) | 2018-01-23 | — | — | US | disclosed |
| US-20160222212-A1 | Asulfonate Discrete PEG Based Dyes | EQUIP, LLC (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160222211-A1 | Fluorescent Probe for Imaging Lymph Nodes | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2016-08-04 | — | — | US | disclosed |
| US-9302018-B2 | Fluorescent probe for imaging lymph nodes | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-04-05 | — | — | US | disclosed |
| US-9095612-B2 | Halogenated compounds for photodynamic therapy | NANOQUANTUM SCIENCES, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20150073154-A1 | Discrete PEG Based Dyes | EQUIP, LLC (US) | 2015-03-12 | — | — | US | disclosed |
| US-20140369935-A1 | LIPOSOME COMPOSITE BODY | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2014-12-18 | — | — | US | disclosed |
| US-8663990-B2 | Measurement method utilizing internal standard substance | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| US-8546586-B2 | Pyrazole-based cyanine dye containing quaternary ammonium cation | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20130129631-A1 | Fluorescent Probe for Imaging Lymph Nodes | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130121926-A1 | DYE COMPOSITIONS AND DYE SYNTHESES | GE HEALTHCARE AS (NO) | 2013-05-16 | — | — | US | disclosed |
| US-20120043207-A1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
| US-20120046474-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129631-A1 | Fluorescent Probe for Imaging Lymph Nodes | PLIN5, LIPA, LY6K | KMT2A 3994/4885ALDH1A1 2279/4885NPC1 50/4885 |
| US-20120046474-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | SLC43A1, HCN4, SLC7A5 | KMT2A 3230/4885ALDH1A1 1828/4885NPC1 2440/4885 |
| US-20160222211-A1 | Fluorescent Probe for Imaging Lymph Nodes | PLIN5, LIPA, LY6K | KMT2A 3994/4885ALDH1A1 2279/4885NPC1 50/4885 |
| US-20150073154-A1 | Discrete PEG Based Dyes | MKI67, MUC1, TP53 | KMT2A 4642/4885ALDH1A1 958/4885NPC1 1923/4885 |
| US-20140369935-A1 | LIPOSOME COMPOSITE BODY | PLIN5, LIPA, NPC1L1 | KMT2A 4081/4885ALDH1A1 1705/4885NPC1 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.