Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19530361 | 1.00 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20881023 | 1.00 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL997093 | 0.98 | KMT2A (0.52) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6259235 | 0.85 | ALDH1A1 (0.52) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5569513 | 0.85 | ALDH1A1 (0.52) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18779752 | 0.85 | ALDH1A1 (0.52) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Benzene SCHEMBL10426584 | 0.85 | ALDH1A1 (0.52) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28544957 | 0.83 | ALDH1A1 (0.50) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20059341 | 0.83 | DHODH (0.43) | KMT2AALDH1A1NPC1SMN1; SMN2NFKB1 | |
| SCHEMBL22808244 | 0.77 | KMT2A (0.53) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117826-A1 | COMPOUNDS AND COMPOSITIONS FOR RETINAL INJURY DETECTION AND METHODS OF USING SAME | MOLECULAR TARGETING TECHNOLOGIES, INC. | 2023-04-20 | — | — | US | disclosed |
| WO-2021158219-A1 | COMPOUNDS AND COMPOSITIONS FOR RETINAL INJURY DETECTION AND METHODS OF USING SAME | MOLECULAR TARGETING TECHNOLOGIES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| EP-2850061-B1 | HALOGENATED INDOLE DERIVATIVES FOR PHOTODYNAMIC THERAPY | NANOQUANTUM SCIENCES INC (US) | 2020-09-16 | — | — | EP | disclosed |
| EP-2983677-A1 | PHOTO-RESPONSIVE COMPOUNDS | The University Of North Carolina At Chapel Hill (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2850061-A2 | HALOGENATED COMPOUNDS FOR PHOTODYNAMIC THERAPY | Nanoquantum Sciences Inc. (US) | 2015-03-25 | — | — | EP | disclosed |
| WO-2014168950-A1 | PHOTO-RESPONSIVE COMPOUNDS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2014-10-16 | — | — | WO | disclosed |
| WO-2013134081-A2 | HALOGENATED COMPOUNDS FOR PHOTODYNAMIC THERAPY | NANOQUANTUM SCIENCES. INC. (US) | 2013-09-12 | — | — | WO | disclosed |
| EP-1874871-B1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LTD (GB) | 2012-10-03 | — | — | EP | disclosed |
| US-8148539-B2 | Cyanine dye labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| EP-1678258-B1 | CYANINE DYE LABELLING REAGENTS | GE HEALTHCARE LTD (GB) | 2011-08-31 | — | — | EP | disclosed |
| US-7750163-B2 | Cyanine dye labelling reagents | GE Healthcare U.K. Limited (GB) | 2010-07-06 | — | — | US | disclosed |
| EP-1874871-A1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE Healthcare UK Limited (GB) | 2008-01-09 | — | — | EP | disclosed |
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | GE HEALTHCARE UK LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
| US-20060239922-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2006-10-26 | — | — | US | disclosed |
| WO-2006111726-A1 | WATER SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | GE HEALTHCARE UK LIMITED (GB) | 2006-10-26 | — | — | WO | disclosed |
| EP-1678258-A1 | CYANINE DYE LABELLING REAGENTS | GE Healthcare Limited (GB) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005044923-A1 | CYANINE DYE LABELLING REAGENTS | GE HEALTHCARE LIMITED (GB) | 2005-05-19 | — | — | WO | disclosed |
| US-20040047806-A1 | Unsymmetrical methine and polymethine dye-molecules for fluorescent intracellular applications | THEODOROPULOS SPYROS (US) | 2004-03-11 | — | — | US | disclosed |
| US-5948608-A | CONTAINING CYANINE DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| US-5723617-A | Pyrrolo 2,1-a!isoquinoline dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040047806-A1 | Unsymmetrical methine and polymethine dye-molecules for fluorescent intracellular applications | MTHFD1, CNDP2, SHMT1 | KMT2A 3381/4885ALDH1A1 2617/4885NPC1 2622/4885 |
| US-20060239922-A1 | WATER-SOLUBLE FLUORO-SUBSTITUTED CYANINE DYES AS REACTIVE FLUORESCENCE LABELLING REAGENTS | TPD52L2, MRPL21, MRPL9 | KMT2A 3156/4885ALDH1A1 2125/4885NPC1 4332/4885 |
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | IK, H1-5, H1-3 | KMT2A 1319/4885ALDH1A1 4348/4885NPC1 4718/4885 |
| US-20230117826-A1 | COMPOUNDS AND COMPOSITIONS FOR RETINAL INJURY DETECTION AND METHODS OF USING SAME | ALDH1A2, PDE6C, ALDH1A3 | KMT2A 4181/4885ALDH1A1 93/4885NPC1 2583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.